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Diversity in Medicine and Science at Upstate: Julio Licinio MD PhD

This subject guide celebrates diversity at Upstate Medical University by highlighting individuals who have made significant contributions to Upstate's mission and to medicine and science in general.

Julio Licinio MD PhD

Julio Licinio MD PhD completed his doctor of medicine degree in 1982 at the University of Bahia School of Medicine in Brazil, where he was first in his class with a score of 99.76 on the entry exam. His residency in medicine was completed at the University of Sao Paulo Medical Center in 1984 and then he moved to the United States for a fellowship in endocrinology at the University of Chicago Pritzker School of Medicine. An internship in psychiatry took Dr. Licinio to the Albert Einstein School of Medicine in the Bronx, NY in 1985 and in 1986 he moved on to New York Hospital-Cornell Medical Center’s Westchester Division for a three year residency in psychiatry.

Dr. Licinio's nearly thirty year career in academic medicine most recently saw him at the South Australian Health and Medical Research Institute where he served as deputy director of translation strategy and process and as the head of the Mind and Brain Theme. He was simultaneously the Matthew Finders Distinguished Professor at Flinders University, also located in Adelaide Australia. He completed his PhD at Flinders University in 2017.

His work with translational medicine was fundamental to his service at UCLA (1999-2006), the University of Miami (2006-2009) and the Australian National University (2009-2013). The many programs, research projects and institutes he helped to build at these institutions were repeatedly funded by the NIH, including the establishment of the UCLA Clinical and Translational Science Institute, which brought together eight clinical departments and six schools, and the Graduate Training Program in Translational Investigation at the University of Miami, which included a master's degree in translational science.

Dr. Lucinio is board certified in psychiatry, is a Fellow of the Royal and New Zealand College of Psychiatrists and the Australian Academy of Health and Medical Sciences. As an NIH-funded researcher his focus has been on depression, stress-related circuits, circadian rhythms, genetics, pharmacology, and pharmacogenomics. He has authored 300 publications and is the founding and current editor-in-chief of Molecular Psychiatry, The Pharmacogenomics Journal, and Translational Psychiatry.

Dr. Licinio’s appointment as senior vice president and dean of the College of Medicine at Upstate on July 1, 2017. He oversees the academic activities of the clinical and basic science departments in the College of Graduate Studies. The degree programs offered span from the MD to the PhD and include and Masters in Public Health. He also oversees research activities of the College of Medicine and serves on the University Executive Council, which sets policy and leads the University at large. Dr. Licinio also holds faculty appointments in the departments of Medicine and Psychiatry.

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Bibliography

1. Bolis CL, Licinio J, van Drimmelen-Krabbe, JJ (eds.). Classification of Dysthymia and Related Conditions in Neurological Disorders: Recommendations for the Clinical Curriculum Vitæ Julio Licinio, M.D. - Page 38 -

Descriptions and Criteria for Research (version for field trials). World Health Organization, Geneva, 1997.

2. Licinio J (ed.). Dysthymia in Neurological Disorders, 1996. Published by the World Health Organization, Division of Mental Health and Prevention of Substance Abuse, Geneva, Switzerland. Authors: Akiskal HS, Bolis CL, Cazzulo C, Costa e Silva JA, Gentil V, Lecrubier Y, Licinio J (Chairman), Linden M, Lopez-Ibor JJ, Ndiaye IP, Pani L, Prilipko L, Robertson M, Robinson RG, Starkstein SE, Thomas P, Wang Y, Wong M-L.

3. Licinio J, Prlipko L, Bolis CL (eds.). Dysthymia in Neurological Disorders - Proceedings of the WHO meeting. World Health Organization, Geneva Switzerland, 1997.

4. Licinio J, Bolis CL, Gold PW (eds.). Dysthymia: From Clinical Neuroscience to Treatment. World Health Organization, Geneva, Switzerland, 1997.

5. Bolis CL, Licinio J (eds.). Stress and the Nervous System. The Advisory Committee on Health Research - World Health Organization, Geneva, Switzerland, 1998.

6. Bolis CL, Licinio J (eds.). Stress and Adaptation: From Selye's Concept to Application of Modern Formulations. World Health Organization, Geneva, Switzerland, 1999.

7. Bolis CL, Licinio J (eds.). Genes, Behaviour and Health. World Health Organization, Geneva, Switzerland, 1999.

8. Bolis CL, Licinio J (eds.). Autonomic Nervous System. World Health Organization, Geneva, Switzerland, 1999.

9. Bolis CL, Licinio J (eds.). Public Health Aspects of Dysthymia in the Field of Neuroscience. World Health Organization, Geneva, Switzerland, 2000.

10. Bolis CL, Pani L, Licinio J (eds.). Dopaminergic System: Its Evolution from Biology to Clinical Aspects. AIREN (International Association for Research and Training in Neurosciences) and World Health Organization, Lippincott Williams & Wilkins Healthcare, Baltimore, MD, 2000.

11. Licinio J, Wong M-L (eds.). Pharmacogenomics: The Search for Individualized Therapies. Wiley-VCH, Weinheim, Germany, 2002, ISBN: 3-527-30380-4, 599 pages.

12. Licinio J, Wong M-L (eds.). Biology of Depression: From Novel Insights to Therapeutic Strategies. Wiley-VCH, Weinheim, Germany, 2005, ISBN: 3-527-30785-0, 1092 pages.

1. Licinio-Paixão J, Polonsky KS, Given BD, Pugh W, Ostrega D, Frank BH, Rubenstein AH: Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide. Journal of Clinical Endocrinology and Metabolism 1986;63:401-403.

2. Polonsky KS, Licinio-Paixão J, Given BD, Pugh W, Rue P, Galloway J, Karrison T, Frank B. Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. Journal of Clinical Investigation 1986;77:98-105.

3. Polonsky KS, Given BD, Pugh W, Licinio-Paixão J, Thompson JE, Karrison T, Rubenstein AH. Calculation of the systemic delivery rate of insulin in normal man. Journal of Clinical Endocrinology and Metabolism 1986;63:113-118.

4. Cohen RM, Given BD, Licinio-Paixão J, Provow SA, Rue PA, Frank BH, Root MA, Polonsky KS, Tager HS, Rubenstein AH. Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism 1986;35:1137-1146.

5. Cohen RM, Licinio J, Polonsky KS, Galloway JA, Frank BH Cherrington AD, Rubenstein AH. The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes. Journal of Clinical Endocrinology and Metabolism 1987;64:476-481.

6. Licinio J, Wong M-L, Gold PW. Localization of interleukin-1 receptor antagonist mRNA in rat brain. Endocrinology 1991;129:562-564.

7. Licinio J, Wong M-L, Gold PW. In situ hybridization histochemistry: A simple and rapid method for the study of peptide gene expression in circulating white blood cells. International Journal of Methods in Psychiatric Research 1991;1:101-1104.

8. Altemus M, Hetherington MM, Flood M, Licinio J, Nelson ML, Bernat AS, Gold PW. Decrease in resting metabolic rate during abstinence from bulimic behavior. American Journal of Psychiatry 1991;148:1071-1072.

9. Wong M-L, Weiss SRB, Gold PW, Doi SQ, Banerjee S, Licinio J, Lad R, Post RM, Smith MA. Induction of constitutive heat shock protein 73 mRNA in the dentate gyrus by seizures. Molecular Brain Research 1992;13:19-25.

10. Paciotti GF, Baron D, Licinio J, Tamarkin L, Wong M-L, Altemus ME, Rubinow D. Novel enzyme immunoassays for the detection of the cytokines interleukin 1alpha and interleukin-2 in the circulation of normal subjects: 24-hour profiles. Progress in NeuroEndocrImmunology 1992;5:21-30.

11. Licinio J, Wong M-L, Gold PW. Neutrophil-Activating Peptide-1/Interleukin-8 mRNA is localized in rat hypothalamus and hippocampus. NeuroReport 1992;3:753-756.

12. Andreason PJ, Altemus M, Zametkin AJ, King AC, Licinio J, Cohen RM. Regional cerebral glucose metabolism in bulimia nervosa. American Journal of Psychiatry 1992;149:1506-1513.

13. Wong M-L, Licinio J, Gold PW, Glowa J. Activity-induced anorexia does not affect the expression of hypothalamic neuropeptide mRNAs. International Journal of Eating Disorders 1993;13:399-405.

14. Wong M-L, Smith MA, Licinio J, Doi SQ, Weiss SRB, Post RM, Gold PW. Glutamate receptor gene expression in kindled and electrically-induced seizures. Epilepsy Research 1993;14:221-227.

15. Licinio J, Seibyl J, Altemus ME, Charney DS, Krystal JH. Elevated central levels of interleukin-2 in neuroleptic-free schizophrenic patients. American Journal of Psychiatry 1993;150:1408-1410.

16. Licinio J, Wong M-L, Altemus M, Bongiorno PB, Bernat A, Tamarkin L, Gold PW. Twenty-four hour concentrations of circulating interleukin-2 in healthy women exhibit episodic fluctuations: analysis of integrated basal levels and discrete pulse properties. Endocrine 1993;1:120-128.

17. Delgado PL, Miller HL, Salomon RM, Licinio J, Heninger GR, Gelenberg AJ, Charney DS. Monoamines and the mechanism of antidepressant action: Effects of catecholamine depletion on mood of patients treated with antidepressants. Psychopharmacology Bulletin 1993;29:389-396.

18. Wong M-L, Licinio J. Localization of interleukin-1 type I receptor mRNA in rat brain. Neuroimmunomodulation 1994;1:110-115.

19. Wong M-L, Licinio J. Localization of stem cell factor mRNA in adult rat hippocampus. Neuroimmunomodulation 1994;1:181-187.

20. Kling MA, Geracioti TD, Licinio J, Michelson D, Oldfield EH, Gold PW. Effects of electroconvulsive therapy on the CRH-ACTH-cortisol system in melancholic depression: Preliminary findings. Psychopharmacology Bulletin 1994;30:489-494.

21. Salomon RM, Delgado PL, Licinio J, Krystal JH, Heninger GR, Charney DS. Effects of sleep deprivation on serotonin function in depression. Biological Psychiatry 1994;36:840-846.

22. Licinio J, Wong M-L, Altemus M, Bongiorno PB, Bernat A, Gold PW. Pulsatility of 24-hour concentrations of circulating interleukin-1alpha in healthy women: Analysis of integrated basal levels, discrete pulse properties, and correlation with simultaneous interleukin-2 concentrations. Neuroimmunomodulation 1994;1:242-250.

23. Wong M-L, Licinio J, Pasternak KI, Gold PW. Localization of corticotropin-releasing hormone receptor mRNA in adult rat brain by in situ hybridization histochemistry. Endocrinology 1994;135:2274-2277.

24. Licinio J, Gold PW, Wong M-L. A molecular mechanism for stress-induced alterations in susceptibility to disease. Lancet 1995;346:104-106.

25. Wong M-L, Loddick SA, Bongiorno PB, Gold PW, Rothwell NJ, Licinio J. Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdala. NeuroReport 1995;6:1785-1788.

26. Licinio J, Bongiorno P, Gold PW, Wong M-L. The gene encoding for the novel transacting factor proopiomelanocortin corticotropin-releasing hormone responsive element binding protein 1 (PCRH-REB-1) is constitutively expressed in rat pituitary and in discrete brain regions containing CRH or CRH receptors: Pathophysiological implications. Endocrinology 1995;136:4709-4712.

27. Wong M-L, Bongiorno P, Gold PW, Licinio J. Localization of interleukin 1ß (IL-1ß) converting enzyme mRNA in rat brain vasculature: Evidence that the genes encoding the IL-1 system are constitutively expressed in brain blood vessels. Pathophysiological implications. Neuroimmunomodulation 1995;2:141-148.

28. Altemus M, Hetherington M, Kennedy B, Licinio J, Gold PW. Thyroid function in bulimia nervosa. Psychoneuroendocrinology 1996;21:249-261.

29. Wong M-L, Al-Shekhlee A, Bongiorno PB, Esposito A, Khatri P, Sternberg ES, Gold PW, Licinio J. Localization of urocortin messenger RNA in rat brain and pituitary. Molecular Psychiatry 1996;1:307-312.

30. Wong M-L, Rettori V, Al-Shekhlee A, Bongiorno PB, Canteros G, McCann SM, Gold PW, Licinio J. Inducible nitric oxide synthase gene expression in the brain during systemic inflammation. Nature Medicine 1996;2:581-584.

31. Wong M-L, Bongiorno PB, Al-Shekhlee A, Esposito A, Khatri P, Gold PW, Licinio J. IL-1ß, IL-1 receptor type I, and iNOS gene expression in rat brain vasculature and perivascular areas. NeuroReport 1996;7:2445-2448.

32. Wong M-L, Khatri P, Licinio J, Esposito A, Gold PW. Identification of hypothalamic transcripts upregulated by antidepressants. Biochemical and Biophysical Research Communications 1996;229:275-279.

33. Wong M-L, Bongiorno PB, Rettori V, McCann SM, Licinio J. Interleukin (IL) 1ß, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: Pathophysiological implications. Proceedings of the National Academy of Sciences USA 1997;94:227-232.

34. Al'Absi M, Bongard S, Buchanan T, Pincomb GA, Licinio J, Lovallo WR. Cardiovascular and neuroendocrine adjustment to public speaking and mental arithmetic stressors.Psychophysiology 1997;34:266-275.

35. Bremner JD, Licinio J, Darnell A, Krystal JH, Owens MJ, Southwick SM, Nemeroff CB, Charney DS. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. American Journal of Psychiatry 1997;154:624-629.

36. Loddick SA, Wong M-L, Bongiorno PB, Gold PW, Licinio J, Rothwell NJ. Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochemical and Biophysical Research Communications 1997;234:211-215.

37. Licinio J, Mantzoros C, Negrão AB, Cizza G, Wong M-L, Bongiorno PB, Chrousos GP, Karp B, Allen C, Flier JS, Gold PW. Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nature Medicine 1997;3:575-579.

38. Cizza G, Lotsikas A, Licinio J, Gold PW, Chrousos GP. Plasma concentrations of leptin in lean controls and patients with Cushing's syndrome before and after correction of hypercortisolism. Journal of Clinical Endocrinology & Metabolism 1997;82:2747-2750.

39. Commerford MC, Licinio J, Halmi KA. Guidelines for discharging eating disorders inpatients. Eating Disorders: The Journal of Treatment and Prevention 1997;5:69-74.

40. Bornstein SR, Licinio J, Tauchnitz R, Engelmann L, Negrão AB, Gold PW, Chrousos G. Plasma leptin levels are increased in survivors of acute sepsis: Associated loss of diurnal rhythm in cortisol and leptin secretion. Journal of Clinical Endocrinology & Metabolism 1998;83:280-283.

41. Licinio J, Negrão AB, Mantzoros C, Kaklamani V, Wong M-L, Bongiorno PB, Mulla A, Cearnal L, Veldhuis JD, Flier JS, McCann SM, Gold PW. Synchronicity of frequentlysampled 24-hour concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women. Proceedings of the National Academy of Sciences USA 1998;95:2541-2546.

42. Pasternak KI, Timo-Iaria C, Rodrigues CJ, Maria DA, Duarte AJS, Paiva L, Pozzi DH, de Mendonça BB, Wong M-L, Licinio J. Circumscribed lesion of the medial forebrain bundle area causes structural impairment of lymphoid organs and severe depression of immune function in rats. Molecular Psychiatry 1998;3:397-404.

43. Licinio J, Negrão AB, Mantzoros C, Kaklamani V, Wong M-L, Bongiorno PB, Negro PP, Mulla A, Cearnal L, Veldhuis JD, Flier JS, McCann SM, Gold PW. Sex differences in circulating human leptin pulse amplitude: Clinical implications. Journal of Clinical Endocrinology & Metabolism 1998;83:4140-4147.

44. Deak T, Nguyen KT, Ehrlich AL, Watkins LR, Spencer RL, Maier SF, Licinio J, Wong ML, Chrousos GP, Webster E, Gold PW. The impact of the nonpeptide corticotropin-releasing Curriculum Vitæ Julio Licinio, M.D. - Page 43 -hormone antagonist antalarmin on behavioral and endocrine responses to stress. Endocrinology 1999;140:79-86.

45. Wong M-L, Webster EL, Spokes H, Phu P, Ehrhart-Bornstein M, Bornstein S, Park C-S,Rice KC, Chrousos GP, Licinio J, Gold PW. Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress. Life Sciences 1999;65:PL53-58.

46. Delgado PL, Miller HL, Salomon RM, Licinio J, Krystal JH, Moreno FA, Heninger GR, Charney DS. Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action. Biological Psychiatry 1999;46:212-220 .

47. Vgontzas AN, Papanicolaou DA, Bixler EO, Lotsikas A, Zachman K, Kales A, Wong M-L, Licinio J, Prolo P, Gold PW, Hermida RC, Mastorakos G, Chrousos GP. Circadian interleukin 6 secretion and quantity and depth of sleep. Journal of Clinical Endocrinology & Metabolism 1999;84:2603-2607.

48. Ozata M, Ozdemir IC, Licinio J. Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects. Journal of Clinical Endocrinology & Metabolism 1999;84:3686-3695.

49. Wong M-L, Kling MA, Munson PJ, Listwak S, Licinio J, Prolo P, Karp B, McCutcheon IE, Geracioti, Jr. TD, DeBellis MD, Rice KC, Goldstein DS, Veldhuis JD, Chrousos PG, Oldfield EH, McCann SM, Gold PW. Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism and corticotropin-releasing hormone. Proceedings of the National Academy of Sciences USA 2000;97:325-330.

50. Wong M-L, Xie B, Beatini N, Phu P, Marathe S, Johns A, Gold PW, Hirsch E, Williams KJ, Licinio J, Tabas I. Acute systemic inflammation up-regulates secretory SMase in vivo: A possible new link between inflammatory cytokines and atherogenesis. Proceedings of the National Academy of Sciences USA 2000; 2000;97:8681-8686.

51. Keenan DM, Licinio J, and Veldhuis JD. A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis. Proceedings of the National Academy of Sciences USA 2001;98;4028-4033.

52. Mantzoros CS, Ozata M, Negrao AB, Ziotopoulou M, Caglayan S, Suchard M, Cogswell RJ, Negro P, Elashoff RM, Liberty V, Wong M-L, Veldhuis JD, Ozdemir IC, Gold PW, Flier JS, Licinio J. Synchronicity of frequently sampled TSH and leptin concentrations in healthy adults and leptin deficient subjects: evidence for possible partial TSH regulation by leptin in humans. Journal of Clinical Endocrinology & Metabolism 2001;86:3284-3291.

53. Hiroi, N, Wong M-L, Licinio J, Parks C, Young M, Gold PW, Chrousos GP, Bornstein SR. Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls. Molecular Psychiatry 2001;6:540-546.

54. Irizarry K, Ma-Li Wong M-L, Licinio J, Lee CJ. Single nucleotide polymorphism identification in candidate gene systems of obesity. The Pharmacogenomics Journal 2001;1:193-203.

55. Kim YK, Suh IB, Kim H, Han C-S, Lim C-S, Choi S-H, Licinio J. The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: effects of psychotropic drugs. Molecular Psychiatry 2002;7:1107-1114.

56. Frost P, Bornstein S, Ehrhart-Bornstein M, O’Kirwan F, Hutson C, Heber D, Go V, Licinio J, and Wong M-L. The prototypic antidepressant drug, imipramine, but not Hypericum perforatum (St John’s Wort), reduces HPA-axis function in the rat. Hormone and Metabolic Research 2003; 35: 602-606.

57. Wong M-L, O'Kirwan F, Khan N, Hannestad J, Wu K, Elashoff D, Lawson G, Gold PW, McCann SM, Licinio J. Identification, characterization, and gene expression profiling of endotoxin-induced myocarditis. Proceedings of the National Academy of Sciences USA 2003;100:14241-14246.

58. Gibbs RA, Belmont JW, Hardenbol P, Willis TD, Yu F, Yang H, Chang LY, Huang W, Liu B, Shen Y, Tam PK, Tsui LC, Waye MM, Wong JT, Zeng C, Zhang Q, Chee MS, Galver LM, Kruglyak S, Murray SS, Oliphant AR, Montpetit A, Hudson TJ, Chagnon F, Ferretti V, Leboeuf M, Phillips MS, Verner A, Kwok PY, Duan S, Lind DL, Miller RD, Rice JP, Saccone NL, Taillon-Miller P, Xiao M, Nakamura Y, Sekine A, Sorimachi K, Tanaka Y, Tsunoda T, Yoshino E, Hunt S, Powell D, Altshuler D, Gabriel SB, Zhang H, Matsuda I, Fukushima Y, Macer DR, Suda E, Rotimi CN, Adebamowo CA, Aniagwu T, Marshall PA, Matthew O, Nkwodimmah C, Royal CD, Leppert MF, Dixon M, Stein LD, Cunningham F, Kanani A, Thorisson GA, Chakravarti A, Chen PE, Cutler DJ, Kashuk CS, Donnelly P, Marchini J, McVean GA, Myers SR, Cardon LR, Abecasis GR, Morris A, Weir BS, Mullikin JC, Feolo M, Daly MJ, Schaffner SF, Qiu R, Kent A, Dunston GM, Kato K, Niikawa N, Knoppers BM, Foster MW, Clayton EW, Wang VO, Watkin J, Sodergren E, Weinstock GM, Wilson RK, Fulton LL, Rogers J, Birren BW, Han H, Wang H, Godbout M, Wallenburg JC, L'Archeveque P, Bellemare G, Todani K, Fujita T, Tanaka S, Holden AL, Lai EH, Collins FS, Brooks LD, McEwen JE, Guyer MS, Jordan E, Peterson JL, Spiegel J, Sung LM, Zacharia LF, Kennedy K, Dunn MG, Seabrook R, Shillito M, Skene B, Stewart JG, Valle DL, Jorde LB, Cho MK, Duster T, Jasperse M, Knoppers BM, Kwok PY, Licinio J, Long JC, Marshall PA, Ossorio PN, Wang VO, Rotimi CN, Royal CD, Spallone P, Terry SF, Lander ES, Lai EH, Nickerson DA, Bentley DR, Boehnke M, Cardon LR, Daly MJ, Deloukas P, Douglas JA, Gabriel SB, Hudson RR, Hudson TJ, Kruglyak L, Kwok PY, Nakamura Y, Nussbaum RL, Royal CD, Sherry ST, Stein LD, Tanaka T (The International HapMap Consortium). The International HapMap Project. Nature 2003;426:789-796.

59. Emergent oscillations in a mathematical model of the human menstrual cycle. Rasgon NL, Pumphrey L, Prolo P, Elman S, MA, Negrao AB, Licinio J, Garfinkel A. CNS Spectrums 2003;8:805-814.

60. Wong M-L, Yildiz BO, Mantzoros CS, Prolo P, Kling M, Flier JS, Gold PW, Licinio J. Simultaneous and continuous twenty-four hour plasma and cerebrospinal fluid leptin measurements: Dissociation of concentrations in central and peripheral compartments. Journal of Clinical Endocrinology & Metabolism 2004;89:258-265.

61. Wong M-L, O'Kirwan F, Hannestad JP, Irizarry KJL, Elashoff D, Licinio J. St. John's wort and imipramine-induced gene expression profiles identify cellular functions relevant to antidepressant action and novel pharmacogenetic candidates for the phenotype of antidepressant treatment response. Molecular Psychiatry 2004; 9:237-251.

62. Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O’Kirwan F, Whitby R, Liang L, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli A, McCann SM, Wong M-L. Phenotypic effects of leptin replacement on behavior, morbid obesity, diabetes mellitus, and hypogonadism in leptin-deficient adults. Proceedings of the National Academy of Sciences USA 2004;101:4531-4536.

63. The International HapMap Consortium (Licinio J, co-author). Integrating ethics and science in the International HapMap Project. Nature Reviews Genetics 2004;5:467-475.

64. Yildiz B, Suchard MA, Wong M-L, McCann SM, Licinio J. Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proceedings of the National Academy of Sciences USA 2004;101:10434-10439 (Recognized by Discover Magazine as one of the top 50 discoveries of 2004).

65. Licinio J, O’Kirwan F, Irizarry K, Merriman B, Thakur S, Jepson R, Lake S, Tantisira KG, Weiss ST, Wong M-L. Association of a corticotropin-releasing hormone receptor 1 haploytype and antidepressant treatment response in Mexican Americans. Molecular Psychiatry 2004;9:1075-1082.

66. LLerena A, Dorado P, O’Kirwan F, Jepson R, Licinio J, Wong, M-L. Lower frequency ofCYP2C9*2 in Mexican-Americans compared to Spaniards. The Pharmacogenomics Journal 2004;4:403-406.

67. Alesci S, Martinez PE, Kelkar S, Ilias I, Ronsaville DS, Listwak SJ, Ayala AR, Licinio J,Gold HK, Kling MA, Chrousos GP, Gold PW. Major depression is associated with significant diurnal elevations in plasma IL-6 levels, a shift of its circadian rhythm, and loss of physiologic complexity in its secretion: Clinical implications. Journal of Clinical Endocrinology & Metabolism 2005;90:2851-2854.

68. Matochik JA, London ED, Yildiz BO, Ozata M, Caglayan S, Depaoli AM, Wong ML, Licinio J. Effect of leptin replacement on brain structure in genetically leptin-deficient adults. Journal of Clinical Endocrinology & Metabolism 2005;90:2851-2854.

69. Williamson DA, Ravussin E, Wong ML, Wagner A, Dipaoli A, Caglayan S, Ozata M, Martin C, Walden H, Arnett C, Licinio J. Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy. Appetite 2005;45:75-80.

70. Gold PW, Wong ML, Goldstein DS, Gold HK, Ronsaville DS, Esler M, Alesci S, Masood A, Licinio J, Geracioti TD Jr, Perini G, DeBellis MD, Holmes C, Vgontzas AN, Charney DS, Chrousos GP, McCann SM, Kling MA. Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia. Proceedings of the National Academy of Sciences USA 2005;102:8303-8308.

71. Dorado P, Caceres MC, Poso-Guisado E, Wong M-L, Licinio J, Llerena A. Development of a PCR-based strategy for CYP2D6 genotyping, including gene multiplication, of potential use worldwide. Biotechniques 2005;39:571-574.

72. Schindler TH, Cardenas J, Prior JO, Facta AD, Kreissl MC, Zhang X-L, Sayre J, Dahlbom M, Licinio J, Schelbert HR. Relationship between increasing body weight, insulin resistance, inflammation, adipocytokine leptin, and coronary circulatory function. Journal of the American College of Cardiology 2006;47(6):1188-1195.

73. Milane MS, Marc A. Suchard MA, Licinio J, Wong M-L. Modeling of the temporal patterns of fluoxetine prescriptions on suicide rates in the United States. PLoS Medicine 2006;3:816-824.

74. Wong ML, Whelan F, Deloukas P, Whittaker P, Delgado M, Cantor RM, McCann SM, Licinio J. Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response. Proceedings of the National Academy of Sciences USA 2006;103:15124-15129.

75. Mastronardi C, Whelan F, Yildiz OA, Hannestad J, Elashoff D, McCann SM, Licinio J, Wong ML. Caspase 1 deficiency reduces inflammation-induced brain transcription. Proceedings of the National Academy of Sciences USA 2007;104:7205-7210.

76. Licinio J, Milane M, Thakur S, Whelan F, Yildiz BO, Delibasi T, de Miranda PB, Ozata M, Bolu E, Depaoli A, Wong M-L. Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight. Appetite 2007;49:594-599.

77. Licinio J, Ribeiro L, Busnello JV, Delibasi T, Thakur S, Elashoff RM, Sharma A, Jardack PM, Depaoli AM, Wong ML. Effects of leptin replacement on macro- and micronutrient preferences. International Journal of Obesity (Lond). 2007;31:1859-1863.

78. Ribeiro L, Busnello JV, Cantor RM, Whelan F, Whittaker P, Deloukas P, Wong ML, Licinio J. The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans. Neuroreport 2007;18:1291-1293.

79. Baicy K, London ED, Monterosso J, Wong ML, Delibasi T, Sharma A, Licinio J. Leptin replacement alters brain response to food cues in genetically leptin-deficient adults. Proceedings of the National Academy of Sciences USA 2007;104:18276-18279.

80. Wong M-L, Dong C, Maestre-Mesa J, Licinio J. Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and treatment response. Molecular Psychiatry 2008;13:800-812.

81. Wong M-L, Dong C, Esposito K, Thakur S, Liu W, Elashoff RM, Licinio J. Elevated stresshemoconcentration in major depression is normalized by antidepressant treatment: secondary analysis from a randomized, double-blind clinical trial and relevance to cardiovascular disease risk. PLoS ONE 2008;3(7): e2350. doi:10.1371/journal.pone.0002350

82. Paz-Filho GJ, Ayala A, Esposito K, Erol HK, Delibasi T, Barry EH, Wong M-L, Licinio J. Effects of leptin on lipid metabolism. Hormone and Metabolic Research 2008;40(8):572-574.

83. Paz-Filho GJ, Andrews D, Esposito K, Erol HK, Delibasi T, Wong M-L, Licinio J. Effects of leptin replacement on risk factors for cardiovascular disease in genetically leptindeficient subjects. Hormone and Metabolic Research 2009;41:164-167.

84. Andreev VP, Paz-Filho GJ, Wong M-L, Licinio J. Deconvolution of insulin secretion, insulin hepatic extraction, post-hepatic delivery rates and sensitivity during 24-hour standardized meals: time course of glucose homeostasis in leptin replacement treatment. Hormone and Metabolic Research 2009;41:142-151.

85. Paz-Filho GJ, Babikian T, Asarnow R, Esposito K, Erol HK, Wong ML, Licinio J. Leptin replacement improves cognitive development. PLoS ONE 2008;3(8):e3098.

86. Paz-Filho GJ, Esposito K, Sharma A, Andreev VP, Delibasi T, Erol HK, Ayala A, Wong ML, Licinio J. Changes in insulin sensitivity during leptin replacement therapy in leptindeficient patients. American Journal of Physiology – Endocrinology and Metabolism 2008;295:E1401-1408.

87. Schwarz PE, Towers GW, van der Merwe A, Perez-Perez L, Rheeder P, Schulze J, Bornstein SR, Licinio J, Wong ML, Schutte AE, Olckers A. Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives. The Pharmacogenomics Journal 2009;9:42-48.

88. Licinio J, Dong C, Wong M-L. Novel sequence variations in the Brain-Derived Neurotrophic Factor gene and association with major depression and antidepressant treatment response. Archives of General Psychiatry 2009;66:488-497.

89. Reierson GW, Mastronardi CA, Licinio, J, Wong M-L. Chronic imipramine downregulates cyclic AMP signaling in rat hippocampus. Neuroreport 2009;20:307-311.

90. Luo H-R, Wu G-S, Dong C, Arcos-Burgos M, Ribeiro L, Licinio J, Wong M-L. Association of PDE11A global haplotype with major depression and antidepressant drug response. Neuropsychiatric Disease and Treatment 2009;5:163-170.

91. Reierson GW, Mastronardi CA, Licinio J, Wong M-L. Repeated antidepressant therapy increases cyclic GMP signaling in rat hippocampus. Neuroscience Letters 2009;466:149-53

92. Dong C, Wong M-L, Licinio J. Sequence variations of ABCB1, SLC6A2,SLC6A3,SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans. Molecular Psychiatry 2009;14:1105-1118.

93. Paz-Filho G, Delibasi T, Erol HK, Wong M-L. Licinio J. Congenital leptin deficiency and thyroid function. Thyroid Research 2009;4:11.

94. Paz-Filho GJ, Delibasi T, Erol HK, Wong ML, Licinio J. Cellular immunity before and after leptin replacement therapy. Journal of Pediatric Endocrinology and Metabolism 2009;22:1069-1074.

95. Reierson GW, Mastronardi CA, Licinio J, Wong M-L. Chronic fluoxetine treatment increases daytime melatonin synthesis in the rodent. Clinical Pharmacology: Advances and Applications 2009;1:1-6.

96. Galgani JE, Greenway FL, Caglayan S, Wong ML, Licinio J, Ravussin E. Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptindeficient patients. Journal of Clinical Endocrinology and Metabolism 2010;95:851-855

97. Mastronardi CA, Licinio J, Wong ML. Candidate biomarkers for systemic inflammatory response syndrome and inflammation: a pathway for novel translational therapeutics. Neuroimmunomodulation 2010;17:359-68.

98. Altshuler DM, Gibbs RA, Peltonen L, Dermitzakis E, Schaffner SF, Yu F, Bonnen PE, de Bakker PIW, Deloukas P, Gabriel SB, Gwilliam R, Hunt S, Inouye M, Jia X, Palotie A, Parkin M, Whittaker P, Chang K, Hawes A, Lewis LR, Ren Y, Wheeler D, Muzny DM, Barnes C, Darvishi K, Hurles M, Korn JM, Kristiansson K, Lee C, McCarroll SA, Nemesh J, Keinan A, Montgomery SB, Pollack S, Price AL, Soranzo N, Gonzaga-Jauregui C, Anttila V, Brodeur W, Daly MJ, Leslie S, McVean G, Moutsianas L, Nguyen H, Zhang Q, Ghori MJR, McGinnis R, McLaren W, Pollack S, Takeuchi F, Grossman SR, Shlyakhter I, Hostetter EB, Sabeti PC, Adebamowo CA, Foster MW, Gordon DR, Licinio J, Manca MC, Marshall PA, Matsuda I, Ngare D, Ota Wang V, Reddy D, Rotimi CN, Royal CD, Sharp RR, Zeng C, Brooks LD, McEwen JE (The International HapMap 3 Consortium). Integrating common and rare genetic variation in diverse human populations. Nature 2010;467:52-58.

99. Dorado P, Sosa-Macias MG, Peñas-Lledó EM, Alanis-Bañuelos RE, Wong ML, Licinio J, Lares-Asseff I, Llerena A. CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards. The Pharmacogenomics Journal 2011;11:108-112.

100. Andreev VP, Dwivedi RC, Paz-Filho G, Krokhin OV, Wong ML, Wilkins JA, Licinio J. Dynamics of plasma proteome during leptin-replacement therapy in genetically based leptin deficiency. The Pharmacogenomics Journal Epub 2010 May 11.

17;22:484.

 

101. Wu GS, Luo HR, Dong C, Mastronardi C, Licinio J, Wong M-L. Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response. Psychiatric Genetics 2011;21:14-18.

102. Mastronardi C, Paz-Filho GJ, Valdez E, Maestre-Mesa J, Licinio J, Wong M-L. Long-term body weight outcomes of antidepressant-environment interactions. Molecular Psychiatry 2011;16:265-272.

103. London ED, Berman SM, Chakrapani S, Delibasi T, Monterosso J, Erol HK, Paz-Filho G, Wong M-L, Licinio J. Short-term plasticity of grey matter associated with leptin deficiency and replacement. Journal of Clinical Endocrinology and Metabolism 2011;96:E1212-20.

104. Schmid J, Ludwig B, Schally AV, Steffen A, Ziegler CG, Block NL, Koutmani Y, Brendel MD, Karalis KP, Simeonovic CJ, Licinio J, Ehrhart-Bornstein M, Bornstein SR. Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11{beta}-hydroxysteroid dehydrogenase. Proceedings of the National Academy of Sciences USA 2011;108:13722-13727.

105. Hornig M, Briese T, Licinio J, Khabbaz RF, Altshuler LL, Potkin SG, Schwemmle M, Siemetzki U, Mintz J, Honkavuori K, Kraemer HC, Egan MF, Whybrow PC, Bunney WE, Lipkin WI. Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder. Molecular Psychiatry 2012;17:486-493.

106. Wong M-L, Dong C, Andreev V, Arcos-Burgos M, Licinio J. Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors. Molecular Psychiatry 2012;17:624-633.

107. Graessler J, Qin Y, Zhong H, Zhang J, Licinio J, Wong M-L, Xu A, Chavakis T, Bornstein AB, Ehrhart-Bornstein M, Lamounier-Zepter V, Lohmann T, Wolf T, Bornstein SR. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: Correlation with inflammatory and metabolic parameters. The Pharmacogenomics Journal 2013;13:514-522.

108. Sosa-Macías M, Lazalde-Ramos BP, Galaviz-Hernández C, Rangel-Villalobos H, Salazar-Flores J, Martínez-Sevilla VM, Martínez-Fierro ML, Dorado P, Wong ML, Licinio J, Llerena A. Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico. The Pharmacogenomics Journal 2013;13:567-572.

109. Berman SM, Paz-Filho G, Wong M-L, Kohno M, Licinio J, London ED. Effects of leptin deficiency and replacement on cerebellar response to food-related cues. Cerebellum 2013;12:59-67.

110. Ullmann E, Barthel A, Licinio J, Petrowski K, Bornstein SR, Strauß B. Increased rate of depression and psychosomatic symptoms in Jewish migrants from the post-Soviet-Union to Germany in the 3rd generation after the Shoa. Translational Psychiatry 2013 Mar 12;3:e241. doi: 10.1038/tp.2013.17.

111. Paz-Filho G, Mastronardi CA, Parker BJ, Khan A, Inserra A, Matthaei K, Ehrhart-Bornstein M, Bornstein S, Wong M-L, Licinio J. Molecular pathways involved in the improvement of nonalcoholic fatty liver disease. Journal of Molecular Endocrinology 2013;51:167-179.

112. Graessler J, Bornstein T, Goel D, Bhalla VP, Lohmann T, Wolf T, Koch M, Qin Y, Licinio J, Wong M-L, Chavakis T, Xu A, Shevchenko A, Schuhmann K, Schwarz PEH, Schulte KM, Patel A, Bornstein SR. Lipidomic profiling before and after Roux-en-Y gastric bypass (RYGB) in obese patients with diabetes. The Pharmacogenomics Journal 2014;14:201-207.

113. Hoang D, Broer N, Roman SA, Yao X, Abitbol N, Li F, Sosa JA, Sue GR, Dewan AT, Wong ML, Licinio J, Simpson C, Li AY, Pizzoferrato N, Narayan D. Leptin signaling and hyperparathyroidism: Clinical and genetic associations. Journal of the American College of Surgeons 2014;218:1239-1250.e4.

114. Paz-Filho G, Boguszewski MC, Mastronardi CA, Patel HR, Johar AS, Chuah A, Huttley GA, Boguszewski CL, Wong ML, Arcos-Burgos M, Licinio J. Whole exome sequencing of extreme morbid obesity patients: translational implications for obesity and related disorders. Genes (Basel) 2014;5:709-725.

115. Wong M-L, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein SR, Arcos-Burgos M, Licinio J. Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in Mexican-Americans. American Journal of Psychiatry 2014;171:1297-1309.

116. Licinio J, Negrão AB, Wong M-L. Plasma leptin concentrations are highly correlated to emotional states throughout the day. Translational Psychiatry 2014 Oct 28;4:e475. doi: 10.1038/tp.2014.115.

117. Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers Jr MG, Licinio J, Brown RD, Enriori PJ, O’Rahilly S, Sternson SM, Spanswick DC, Grove JL, Farooqi IS, Cowley MA. Leptin mediates the increase in blood pressure associated with obesity. Cell 2014;159:1404-1416.

118. Mastronardi CA, Paz-Filho G, Zanoni M, Molano-González N, Arcos-Burgos M, Licinio J,Wong ML. Temporal gene expression in the hippocampus and peripheral organs to endotoxin-induced systemic inflammatory response in caspase-1-deficient mice. Neuroimmunomodulation 2015;22:263-273.

119. Vukićević V, Qin N, Balyura M, Eisenhofer G, Wong M-L, Licinio J, Bornstein SR, Ehrhart-Bornstein M. Valproic acid enhances neuronal differentiation of sympathoadrenal progenitor cells. Molecular Psychiatry 2015;20:941–950.

120. Perry Y, Calear AL, Mackinnon A, Batterham PJ, Licinio J, King C, Thomsen N, Scott J, Donker T, Merry S, Fleming T, Stasiak K, Werner-Seidler A, Christensen H. Trial for the Prevention of Depression (TriPoD) in final-year secondary students: study protocol for a cluster randomised controlled trial. Trials 2015;16(1):451. doi:10.1186/s13063-015-0929-1.

121. Gold PW, Pavlatou MG, Michelson D, Mouro CM, Kling MA, Wong M-L, Licinio J, Goldstein SA. Chronic administration of anticonvulsants but not antidepressants impairs bone strength: clinical implications. Translational Psychiatry 2015;5:e576. doi:10.1038/tp.2015.38.

122. Wong M-L, Inserra A, Lewis MD, Mastronardi CA, Leong L, Choo J, Kentish S, Xie P, Morrison M, Wesselingh SL, Rogers GB, Licinio J. Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition. Molecular Psychiatry 2016;21:797-805.

123. Zheng P, Zeng B, Zhou C, Liu M, Fang Z, Xu X, Zeng L, Chen J, Fan S, Du X, Zhang X, Yang D, Yang Y, Meng H, Li W, Melgiri ND, Licinio J, Wei H, Xie P. Altered gut microbiome induces depressive-like behaviors through a pathway mediated by the host’s metabolism. Molecular Psychiatry 2016;21:786-796.

124. Xiu MH, Tian L, Chen S, Tan YL, Chen DC, Chen J, Chen N, De Yang F, Licinio J, Kosten TR, Soares JC, Zhang XY. Contribution of IL-10 and its -592 A/C polymorphism to cognitive functions in first-episode drug-naive schizophrenia. Brain Behavior & Immununity 2016 Mar 10. pii: S0889-1591(16)30050-2. doi: 10.1016/j.bbi.2016.03.005.

125. Kan C, Pedersen NL, Christensen K, Bornstein SR, Licinio J, MacCabe JH, Ismail K, Rijsdijk F. Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registries. Molecular Psychiatry 2016;21:903-909.

126. Vélez JI, Lopera F, Sepulveda-Falla D, Patel HR, Johar AS, Chuah A, Tobón C, Rivera D, Villegas A, Cai Y, Peng K, Arkell R, Castellanos FX, Andrews SJ, Silva Lara MF, Creagh PK, Easteal S, de Leon J, Wong M-L, Licinio J, Mastronardi CA, Arcos-Burgos M. APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease. Molecular Psychiatry 2016;21:916-924.

127. Pollok J, van Agteren JEM, Carson KV, Esterman AJ, Smith BJ, Licinio J. Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2016, Issue 9. Art. No.: CD012347. DOI: 10.1002/14651858.CD012347.

128. Naqvi SS, Pollok J, van Agteren JEM, Usmani ZA, Carson KV, Smith BJ, Licinio J. Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews. 2016, Issue 9. Art. No.:CD012346. DOI: 10.1002/14651858.CD012346.

129. Stojakovic A, Paz-Flho G, Arcos-Burgos M, Licinio J, Wong M-L, Mastronardi CA. Role of the IL-1 pathway in dopaminergic neurodegeneration and decreased voluntary movement. Molecular Neurobiology 2017;54:4486-4495.

130. Wong M-L, Arcos-Burgos M, Liu S, Velez JI, Yu C, Baune BT, Jawahar MC, Arolt V, Dannlowski U, Chuah A, Huttley GA, Fogarty R, Lewis M, Bornstein SR and Licinio J. The PHF21B gene is associated with major depression, and modulates the stress response. Molecular Psychiatry 2017;22:1015-1025.

131. Bacchi S, Licinio J. Resilience and psychological distress in psychology and medical students. Academic Psychiatry 2017;41:185-188.

132. Yu C, Baune BT, Licinio J, Wong M-L. Whole-genome single nucleotide variant distribution on genomic regions and its relationship to major depression. Psychiatry Research 2017;252:75-79.

133. Yu C, Baune BT, Licinio J, Wong M-L. Single-nucleotide variant proportion in genes: a new concept to explore major depression based on DNA sequencing data. Journal of Human Genetics 2017;62:577-580.

134. Yu C, Baune BT, Licinio J, Wong ML. A novel strategy for clustering major depression individuals using whole-genome sequencing variant data. Scientific Reports 2017 Mar 13;7:44389. doi: 10.1038/srep44389.

135. Ullmann E, Licinio J, Barthel A, Petrowski K, Oratovski B, Stalder T, Kirschbaum C, Bornstein SR. Circumcision does not alter long-term glucocorticoids accumulation or psychological effects associated with trauma- and stressor-related disorders. Translational Psychiatry 2017 Mar 14;7(3):e1063. doi: 10.1038/tp.2017.23.

136. Yu C, Arcos-Burgos M, Licinio J, Wong ML. A latent genetic subtype of major depression identified by whole-exome genotyping data in a Mexican-American cohort. Translational Psychiatry 2017 May 16;7(5):e1134. doi: 10.1038/tp.2017.102.

137. Mishra AK, Parish CR, Wong M-L, Licinio J, Blackburn AC. Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer. PLoS ONE 2017;12(5):e0178454. https://doi.org/10.1371/journal.pone.0178454.

138. Graessler J, Mehnert CS, Schulte KM, Bergmann S, Strauss S, Bornstein TD, Licinio J, Wong ML, Birkenfeld AL, Bornstein SR. Urinary Lipidomics: evidence for multiple sources and sexual dimorphism in healthy individuals. The Pharmacogenomics Journal 2017 Jun 13. doi: 10.1038/tpj.2017.24. [Epub ahead of print]

139. Ullmann E, Licinio J, Barthel A, Petrowski K, Stalder T, Bornstein SR, Kirschbaum C. Persistent LHPA activation in german individuals raised in an overprotective parental behavior. Scientific Reports 2017;7(1):2778. doi: 10.1038/s41598-017-01718-z.

140. Yu C, Baune BT, Wong ML, Licinio J. Investigation of copy number variation in subjects with major depression based on whole-genome sequencing data. Journal of Affective Disorders 2017;220:38-42.

141. Taylor AW, Kelly G, Dal Grande E, Kelly D, Marin T, Hey N, Burke KJ, Licinio J. Population levels of wellbeing and the association with social capital. BMC Psychology 2017 Jul 3;5(1):23. doi: 10.1186/s40359-017-0193-0.

142. Shi Z, Atlantis E, Taylor AW, Gill TK, Price K, Appleton S, Wong ML, Licinio J. SSRI antidepressant use potentiates weight gain in the context of unhealthy lifestyles: results from a 4-year Australian follow-up study. BMJ Open 2017 Aug 11;7(8):e016224. doi: 10.1136/bmjopen-2017-016224.

143. Yu C, Baune BT, Fu KA, Wong ML, Licinio J. Genetic clustering of depressed patients and normal controls based on single-nucleotide variant proportion. Journal of Affective Disorders 2017;227:450-454.

144. Yu C, Arcos-Burgos M, Baune B, Arolt V, Dannlowski U, Wong ML, Licinio J. Lowfrequency and rare variants may contribute to elucidate the genetics of major depressive disorder. Translational Psychiatry [in press].

145. Yu C, Baune BT, Fu KA, Wong ML, Licinio J. Investigation of short tandem repeats in major depression using whole-genome sequencing data [in review]. Letters

146. Bornstein SR, Torpy DJ, Chrousos GP, Licinio J, Engelmann L. Leptin levels are elevated despite low thyroid hormone levels in the "euthyroid sick" syndrome. Journal of Clinical Endocrinology & Metabolism 1997;82:4278-4279.

147. Licinio J. Longitudinally sampled human plasma leptin and cortisol concentrations are inversely correlated. Journal of Clinical Endocrinology & Metabolism 1998;83:1042.

148. Licinio J, Wong M-L. Depression and obesity treatments are life-saving. Nature Medicine 2002;8:1336.

149. Flores DL, Alvarado I, Wong M-L, Licinio J, Flockhart D. Clinical implications of genetic polymorphism of CYP2D6 in Mexican Americans. Annals of Internal Medicine 2004;140:W48-49.

150. Irizarry K, Licinio J. An explanation for the placebo effect. Science 2005;307:1411-1412.

151. Korenblum W, Barthel A, Licinio J, Wong ML, Wolf OT, Kirschbaum C, Bornstein SR. Elevated cortisol levels and increased rates of diabetes and mood symptoms in Soviet Union-born Jewish immigrants to Germany. Molecular Psychiatry 2005;10:974-975.

152. Reichel A, Schwarz J, Schulze J, Licinio J, Wong ML, Bornstein SR. Depression and anxiety symptoms in diabetic patients on continuous subcutaneous insulin infusion (CSII). Molecular Psychiatry 2005;10:975-976.

153. Prado-Lima PS, Cruz IB, Schwanke CH, Netto CA, Licinio J. Human food preferences are associated with a 5-HT(2A) serotonergic receptor polymorphism. Molecular Psychiatry 2006;11:889-891.

154. Sharma A, Busnello JV, Ribeiro L, Thakur S, Whelan F, Elashoff R, Wong M-L, Licinio J. Suicidality scores during double-blind fluoxetine and desipramine treatment in Mexican- Americans. Journal of Clinical Psychopharmacology 2007;27:99-101.

155. Paz-Filho GJ, Busnello JV, Licinio J, Zelmanovitz F. Radioiodine treatment triggers security alarms: case report and review of literature. Journal of Nuclear Medicine 2008;49:337.

156. Paz-Filho GJ, Esposito K, Sharma A, Andreev VP, Delibasi T, Erol HK, Ayala A, Wong ML, Licinio J. Reply to Oral and Burant. American Journal of Physiology – Endocrinology and Metabolism 2009; 296: doi: 10.1152/ajpendo.90939.2008.

157. Paz-Filho G, Wong ML, Licinio J. Leptin levels and Alzheimer disease. JAMA 2010 Apr 21;303(15):1478; author reply 1478-9.

158. Licinio J, Easteal S, Wong M-L. Concrete helix recalls smallpox win. Nature 2010;468:173.

159. Ishibashi K, Berman SM, Paz-Filho G, Lee B, Robertson C, Mandelkern MA, Wong ML, Licinio J, London ED. Dopamine D(2)/D(3) receptor availability in genetically leptindeficient patients after long-term leptin replacement. Molecular Psychiatry 2012;17:52-53.

160. Licinio J, Wong W-L. US shutdown should spur other nations. Nature 2013;503-198.

161. Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J. Response to Uher et al. American Journal of Psychiatry 2015;172:396-398.

162. Irizarry K, Merriman B, Bahamode M, Wong M-L, Licinio J. The evolution of signaling complexity suggests a mechanism for reducing the genomic search space in human association studies. Molecular Psychiatry 2005:10:14-26.

163. Licinio J. The experience of bipolar disorder: a personal perspective on the impact of mood disorder symptoms. Molecular Psychiatry 2005;10:827-830.

164. Bornstein SR, Wong ML, Licinio J. 150 years of Sigmund Freud: What would Freud have said about the obesity epidemic? Molecular Psychiatry 2006;11:1070-1072.

165. Oquendo MA, Canino G, Lehner T, Licinio J. Genetic repositories for the study of major psychiatric conditions: what do we know about ethnic minorities' genetic vulnerability? Molecular Psychiatry 2010; 15:970-975.

166. Ullmann E, Barthel A, Tache S, Bornstein A, Licinio J, Bornstein SR. Emotional and psychological trauma in refugees arriving in Germany in 2015. Molecular Psychiatry 2015;20:1483-1484.

167. Rubin de Celis MF, Bornstein SR, Androutsellis-Theotokis A, Andoniadou CL, Licinio J, Wong ML, Ehrhart-Bornstein M. The effects of stress on brain and adrenal stem cells. Molecular Psychiatry 2016;21:590–593.

168. Licinio J, Wong M-L: Monika Ehrhart-Bornstein, 1959-2015. Molecular Psychiatry 2016;21:588–589.

169. Bidargaddi N, Musiat P, Makinen VP, Ermes M, Schrader G, Licinio J. Digital footprints: facilitating large-scale environmental psychiatric research in naturalistic settings through data from everyday technologies. Molecular Psychiatry 2017;22:164-169.

170. Allison S, Bastiampillai T, Licinio J, Fuller DA, Bidargaddi N, Sharfstein SS. When should governments increase the supply of psychiatric beds? Molecular Psychiatry 2017 Jul 11. doi: 10.1038/mp.2017.139. [Epub ahead of print]

171. Licinio-Paixão J. Hyperinsulinemia; a mediator of decreased food intake and weight loss in anorexia nervosa and major depression. Medical Hypotheses 1989;28:125-130.

172. Licinio J, Gold PW. The role of CRH 41 in depressive illness. Baillière’s Clinical Endocrinology and Metabolism 1991;5:51-58.

173. Delgado PL, Price LH, Miller HL, Salomon RM, Licinio J, Krystal JH, Heninger GR, Charney DS. Rapid serotonin depletetion as a provocative challenge test for patients with major depression: Relevance to antidepressant action and the neurobiology of depression. Psychopharmacology Bulletin 1991;27:321-330.

174. Miller HL, Delgado PL, Salomon RM, Licinio J, Barr LC, Charney DS. Acute tryptophan depletion: A method of studying antidepressant action. Journal of Clinical Psychiatry 1992;53:28-35 (suppl.).

175. Wong M-L, Gold PW, Licinio J. In situ hybridization techniques for the localization of interleukin-1 and interleukin-1 receptor antagonist mRNA in brain. Methods in Neurosciences 1993;16:81-99.

176. Licinio J, Wong M-L, Gold PW. The hypothalamic-pituitary-adrenal axis in anorexia nervosa. Psychiatry Research 1996;62:75-83.

177. Licinio J, Wong M-L. Interleukin 1ß and fever. Nature Medicine 1996;2:1314-1315.

178. Akiskal HS, Bolis CL, Cazzulo C, Costa e Silva JA, Gentil V, Lecrubier Y, Licinio J, Linden M, Lopez-Ibor JJ, Ndiaye IP, Pani L, Prilipko L, Robertson MM, Robinson RG, Starkstein SE, Thomas P, Wang Y, Wong M-L. Dysthymia in neurological disorders. Molecular Psychiatry 1996;1:478-491.

179. Licinio J. Breaking the patterns of depression (Book Review). Nature Medicine 1997;3:354.

180. Licinio J. Central nervous system cytokines and their relevance for neurotoxicity and apoptosis. Journal of Neural Transmission 1997;49 (suppl):169-175.

181. Licinio J, Wong, M-L. Pathways and mechanisms for cytokine signalling of the central nervous system. Journal of Clinical Investigation 1997;100:2941-2947.

182. Licinio J. The Biology and Psychology of Depression. Dolentium Hominum 1997;34:116-120.

183. Licinio J, Wong M-L. Interleukin 1 receptor antagonist gene expression in rat pituitary in the systemic inflammatory response syndrome: Pathophysiological implications. Molecular Psychiatry 1997.99-103.

184. Licinio J, Kling MA, Hauser P. Cytokines and brain function: Relevance to a-interferoninduced mood and cognitive changes. Seminars in Oncology 1998;25 (suppl):30-38.

185. Prolo P, Wong M-L, Licinio J. Molecules in focus: Leptin. International Journal of Biochemistry and Cell Biology 1998;30:1285-90.

186. Licinio J. Expressing Freudian influences (review of the US Library of Congress exhibit Freud - Conflict and Culture). Science 1998;282:2197-2198.

187. McCann SM, Licinio J, Wong M-L, Yu WH, Karanth S, Rettori V. The nitric oxide hypothesis of aging. Experimental Gerontology 1998;33:813-826.

188. Prolo P, Licinio J. Cytokines in affective disorders and schizophrenia: New clinical and genetic findings. Molecular Psychiatry 1999;4:109-111

189. Licinio J, Prolo P, McCann SM, Wong M-L. Brain iNOS - current understanding and clinical implications. Molecular Medicine Today 1999;5:225-232.

190. Licinio J, Wong M-L. The role of inflammatory mediators in the biology of major depression: Central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection . Molecular Psychiatry 1999;4:317-327.

191. Licinio J. What Makes One Tic? (Book Review). Science 1999;286:56-57.

192. Negrão AB, Licinio J. (Mental health in the next decade). Revista USP 1999;43:60-69.

193. Negrão AB, Licinio J. Obesity: on the eve of a major conceptual revolution. Drug Discovery Today 2000;5:177-179.

194. Licinio J, Frost P. The neuroimmune-endocrine axis: pathophysiological implications for central nervous system cytokines and hypothalamus-pituitary-adrenal hormone dynamics. Braz J Med Biol Res 2000;33:1141-1148.

195. Licinio J. Pharmacogenomics and Ethnic Minorities. Psychiatric Times 2000;17:47-52.

196. Negrão AB, Licinio J. [Leptin: the dialogue between adipocytes and neurons]. Brazilian Archives of Endocrinology and Metabolism 2001;7:42-48.

197. Licinio J. An Internet Tea Party. (Book Review). Science 2001; 291:1493-1495.

198. Wong M-L, Licinio J. Research and treatment approaches to depression. Nature Reviews Neuroscience 2001;2:343-351.

199. Licinio J, Wong M-L. Clinical implications: The pharmacogenomics of depression. The Pharmacogenomics Journal 2001;1:175-177.

200. Wong M-L, Frost PJ, Hannestad JP, Licinio J. Mechanisms of Brain-Body Communication: How the brain regulates disease susceptibility and feeling ill? Biotechnology International III (Universal Medical Press, San Francisco, CA) 2001:173-180.

201. Wong M-L, Hannestad JP, Licinio J. Pharmacogenomics of Antidepressants: Drug Discovery, Treatment, and Ethical Considerations. The Economics of Neuroscience 2002;4:32-36.

202. Licinio J. Leptin: Endocrine effects of an adipocyte hormone that promotes homeostasis. Progress in Obesity Research 2003;9:739-743.

203. Wong M-L, Licinio J. From monoamines to genomic targets: A paradigm shift for drug discovery in depression. Nature Reviews Drug Discovery 2004;3:136-151.

204. Kirchheiner J, Nickchen K, Bauer M, Wong M-L, Licinio J, Roots I, Brockmöller J. Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response. Molecular Psychiatry 2004;9:442-473.

205. Licinio J, Wong M-L: Antidepressants, depression, and suicidality: A critical appraisal. Nature Reviews Drug Discovery 2005;4:165-171.

206. Gurwitz D, Lunshof JE, Dedoussis G, Flordellis CS, Fuhr U, Kirchheiner J, Licinio J, Llerena A, Manolopoulos VG, Sheffield LJ, Siest G, Torricelli F, Vasiliou V, Wong S. Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education. The Pharmacogenomics Journal 2005;5(4):221-225.

207. Bornstein SR, Schuppenies A, Wong ML, Licinio J. Approaching the shared biology of obesity and depression: the stress axis as the locus of gene-environment interactions. Molecular Psychiatry 2006;11:892-902.

208. Licinio J, Mastronardi C, Wong M-L. Pharmacogenomics of neuroimmune interactions in human psychiatric disorders. Experimental Physiology 2007;92:807-811.

209. Schwarz PE, Reimann M, Li J, Bergmann A, Licinio J, Wong M-L, Bornstein SR. The metabolic syndrome - a global challenge for prevention. Hormone & Metabolic Research 2007;39:777-780.

210. Bornstein SR, M. Ehrhart-Bornstein M, Wong M-L, Licinio J. Is the worldwide epidemic of obesity a communicable feature of globalization? Experimental and Clinical Endocrinology and Diabetes 2008;116 (Suppl.1):S30–S32.

211. Mastronardi C, Licinio J, Wong M-L. A Tribute to Dr. Samuel McDonald McCann’s life as a scientist, mentor and friend. Physiological Mini-Reviews 2009;4: 49-55.

212. Esposito K, Reierson GW, HR, Wu GS, Licinio L, Wong M-L. Phosphodiesterase genes and antidepressant treatment response. Annals of Medicine 2009;41:177-185.

213. Paz-Filho G, Licinio J, Wong ML. Pathophysiological basis of cardiovascular disease and depression: a chicken-and-egg dilemma. Revista Brasileira de Psiquiatria 2010;32:181-191.

214. Paz-Filho G, Wong M-L, Licinio J. The procognitive effects of leptin in the brain and their clinical implications. International Journal of Clinical Practice 2010;64:1808-1812.

215. Paz-Filho G, Mastronardi C, Delibasi T, Wong M-L, Licinio J. Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy. Arquivos Brasileiros de Endocrinologia e Metabolismo 2010;54:690-697.

216. Paz-Filho G, Lim EL, Wong M-L, Licinio J. Associations between adipokines and obesityrelated cancer. Frontiers in Bioscience 2011;16:1634-1650.

217. Paz-Filho G, Wong M-L, Licinio J. Ten years of leptin replacement therapy. Obesity Reviews 2011 May;12(5):e315-23. doi: 10.1111/j.1467-789X.2010.00840.x.

218. Licinio J, Wong M-L. Pharmacogenomics of antidepressant treatment effects. Dialogues in Clinical Neuroscience 2011;13:63-71.

219. Bornstein SR, Licinio J. Improving the efficacy of translational medicine by optimally integrating health care, academia and industry. Nature Medicine 2011;17:1567-1569.

220. Bornstein SR, Ehrhart-Bornstein M, Androutsellis-Theotokis A, Eisenhofer G, Vukicevic V, Licinio J, Wong M-L, Calissano P, Nisticò G, Preziosi P, Levi-Montalcini R. Chromaffin cells: the peripheral brain. Molecular Psychiatry 2012;17:354-358

221. Reierson GW, Guo S, Mastronardi C, Licinio J, Wong M-L. cGMP signaling, phosphodiesterases and major depressive disorder. Current Neuropharmacology 2011;9:715-727.

222. Paz-Filho G, Mastronardi C, Franco CB, Wang KB, Wong M-L, Licinio J. Leptin: molecular mechanisms, systemic pro-inflammatory effects, and clinical implications. Arquivos Brasileiros de Endocrinologia e Metabolismo. 2012;56:597-607.

223. Paz-Filho G, Mastronardi C, Wong ML, Licinio J. Leptin therapy, insulin sensitivity, and glucose homeostasis. Indian Journal of Endocrinology & Metabolism 2012;16:S549-55

224. Gold PW, Licinio J, Pavlatou. Pathological parainflammation and endoplasmic reticulum stress in depression: Potential translational targets through the CNS insulin, klotho, and PPAR-g systems. Molecular Psychiatry 2013;18:154-165.

225. Licinio J. Diagnosing madness. Science 2013;340:1406-1407.

226. Paz-Filho G, Mastronardi CA, Licinio J. Leptin treatment: Facts and expectations. Metabolism 2014 Aug 3. pii: S0026-0495(14)00234-0. doi: 10.1016/j.metabol.2014.07.014. [Epub ahead of print].

227. Bacchi S, Licinio J. Qualitative literature review of the prevalence of depression in medical students compared to students in non-medical degrees. Academic Psychiatry 2014 Nov 15 [Epub ahead of print]. doi: 10.1007/s40596-014-0241-5.

228. Lee SH, Paz-Filho G, Mastronardi C, Licinio J, Wong M-L. Is increased antidepressant exposure a contributory factor to the obesity pandemic? Translational Psychiatry (2016) 6:e759; doi:10.1038/tp.2016.25. Published online 15 March 2016.

229. Rogers GB, Keating DJ, Young RL, Wong M-L, Licinio J, Wesselingh S. From gut dysbiosis 1 to altered brain function and mental illness: mechanisms and pathways. Molecular Psychiatry 2016;21:738-748.

230. Licinio J, Wong M-L, Gold PW. Interactions between thyroid hormones and other endocrine systems. In Joffe RT, Levitt AJ, eds. The Thyroid Axis and Psychiatric Illness, American Psychiatric Press: Washington, D.C., 1993, pp 133-146.

231. Charney DS, Miller H, Licinio J, Salomon RM. Treatment of depression. In The American Psychiatric Press Textbook of Psychopharmacology, American Psychiatric Press: Washington, D.C., 1995, pp 575-601

232. Sternberg EM, Licinio J. Overview of neuroimmune stress interactions. Implications for susceptibility to inflammatory disease. Annals of the New York Academy of Sciences 1995;771:364-371.

233. Gold PW, Licinio J, Wong ML, Chrousos GP. Corticotropin releasing hormone in the pathophysiology of melancholic and atypical depression and in the mechanism of action of antidepressant drugs. Annals of the New York Academy of Sciences 1995;771:716-729.

234. Michelson D, Licinio J, Gold PW. Mediation of stress by the hypothalamic-pituitary-adrenal axis. In: Friedman MJ, Charney DS, Deutch AY, eds. Neurobiological and Clinical Consequences of Stress: From Normal Adaptation to Post-Traumatic Stress Disorder. Raven Press, New York, 1995.

235. Licinio J, Sternberg EM. Neuroendocrine-immune interactions: The role of HPA/IL-1 function in disease susceptibility. In Kaplan H, Gass GH, eds. Handbook of Endocrinology, CRC Press: Boca Raton, 1996, pp 261-269.

236. Wong M-L, Al-Shekhlee A, Gold PW, Licinio J. Cytokines in the brain. In Rothwell NJ, ed. Cytokines in the Nervous System, Landers Bioscience Publishers, Georgetown, Texas, 1996, pp 3-20.

237. Licinio J, Gold PW: Neuroendocrine alterations in dysthymia. In Licinio J, Bolis CL, Gold PW, eds. Dysthymia: From Clinical Neuroscience to Treatment. World Health Organization, Geneva Switzerland, 1997, pp 54-62.

238. Licinio J, Gold PW. The Neuroendocrinology of dysthymia. In Licinio J, Prilipko L, Bolis CL, eds. Dysthymia in Neurological Disorders. World Health Organization, Geneva, 1997, pp 37-46.

239. Licinio J, Gold PW. Frontiers in neuroendocrinology. In Neuroscience, Neurology, and Health. The Advisory Committee on Health Research, World Health Organization, Geneva, 1997, pp 105-128.

240. Licinio J. Neurobiology of stress. In Bolis CL, Licinio J, eds. Stress and the Nervous System. The Advisory Committee on Health Research - World Health Organization, Geneva, Switzerland, 1998, pp 3-13.

241. Licinio J. Molecular neuroendocrinology and its impact on behavior. In Bolis CL, Licinio J, eds. Genes, Behaviour and Health. World Health Organization, Geneva, 1998, pp 37-60.

242. Licinio J, Prolo P. Homeostatic processes in neuroendocrinology. In Bolis CL, Licinio J, eds. Stress and Adaptation: From Selye's Concept to Application of Modern Formulations. World Health Organization, Geneva, 1999, pp 27-36.

243. Licinio J. The autonomic nervous system and its impact on neuroendocrine regulation. In Bolis CL, Licinio J, eds. The Autonomic Nervous System. World Health Organization, Geneva, 1999, pp 53-65.

244. Licinio J. Dysthymia: Results of an international multicentre study. In Bolis CL, Licinio J, eds. Public Health Aspects of Dysthymia in the Field of Neuroscience. World Health Organization, Geneva, 2000, pp39-59.

245. Licinio J. The endocrinology of aging. In C.L. Bolis, G. Ayala, E.R. Weibel, S.H. Maddrell. International Society of Biological Membranes CD-ROM, Oasi Editrice, 2000.

246. Prolo P, Licinio J. D4DR and novelty seeking. In Benjamin J, Ebstein R, Belmaker RH eds. Molecular Genetics and the Human Personality. American Psychiatric Press, Washington, DC, 2002.

247. Licinio J. The role of dopamine in the response to stress. In Bolis CL, Pani L, Licinio J (eds.). Dopaminergic System: Evolution from Biology to Clinical Aspects. AIREN (International Association for Research and Training in Neurosciences) and World Health Organization, Lippincott Williams & Wilkins Healthcare, Baltimore, MD, 2001.

248. Licinio J. Cytokines in the brain: From localization and function to clinical implications. In Berczi I, Gorczynski RM (eds). New Foundation of Biology: Volume I. Neuroimmune Biology. Elsevier, Amsterdam, The Netherlands, 2001, pp 365-371.

249. Negrão AB, Licinio J. Anorexia nervosa and bulimia nervosa. In Arnold A, Etgen A, Rubin R (ed.) Hormones, Brain and Behavior, section: Endocrinologically important behavioral syndromes. Academic Press, San Diego, 2002, pp-515-530.

250. Wong M-L, Alvarado I, Licinio J. Pharmacogenomics of major depression and antidepressant treatment. In Licinio J, Wong M-L (eds.) Pharmacogenomics: The Search for Individualized Therapies. Wiley-VCH, Weinheim, Germany, 2002, pp 379-396.

251. Licinio J, Wong M-L. Cytokine pathways in the brain. In Kronfol Z. (ed.) Cytokines and Mental Health. Kluwer Academic Publishers, Dordrecht, The Netherlands and New York, USA, 2003.

252. Licinio J, Wong M-L. Pharmacogenomic approaches to common and complex disorders: The paradigm of psychopharmacology. In McGraw-Hill Yearbook of Science & Technology. McGraw-Hill, New York, 2003.

253. Licinio J. Psychopharmacology in Children and Adolescents. In Neonatal and Pediatric Pharmacology (SJ Yaffe and JV Aranda, eds), Lippincott Williams & Wilkins: Philadelphia, 2005, pp 520-526.

254. Licinio J, Wong M-L. Emerging treatments for depression: Beyond the monoamine hypothesis. In Licinio J, Wong M-L (eds.). Biology of Depression: From Novel Insights to Therapeutic Strategies. Wiley-VCH, Weinheim, Germany, 2005, pp 943-962.

255. Licinio J, Wong M-L. Antidepressants and suicide: Clinical considerations. In Licinio J, Wong M-L (eds.). Biology of Depression: From Novel Insights to Therapeutic Strategies. Wiley-VCH, Weinheim, Germany, 2005, pp 963-976.

256. Paz-Filho GJ, Licinio J. Anorexia nervosa and bulimia nervosa. In Arnold A, Etgen A, Rubin R (ed.) Hormones, Brain and Behavior, section: Endocrinologically important behavioral syndromes. Academic Press, San Diego, 2008.

257. Paz-Filho GJ, Mishra AK, Licinio J. Adipokines: Soluble factors from adipose tissue implicated in cancer. In Kolonin MG (ed.). Adipose Tissue and Cancer. Springer, Berlin, Germany, 2013.

258. Bolis CL, Abraham G, Araki S, Brambilla F, Brewerton T, Casper R, Halmi K, Herholz K, Kaye W, Kuboki T, Licinio J, Magistretti P, Mueller E, Negrão A, Ndiaye P, Pirke K, Suematsu H, Thomas PK, Wakeling T, Zhou DF. Anorexia nervosa: Directions for future research. International Journal of Eating Disorders 1995;17:235-241.

259. Licinio J, Magistretti P, Bolis CL. Introduction. The World Health Organization sponsored Study Group on Anorexia Nervosa (AN): Basic mechanisms, clinical approaches and treatment. Psychiatry Research 1996;62:1-2.

260. Licinio J. Molecular Psychiatry: The integration of molecular medicine and clinical psychiatry. Molecular Psychiatry 1996;1:1-3.

261. Licinio J. The dopamine D4 receptor and attention deficit hyperactivity disorder. Molecular Psychiatry 1996;1:83-84.

262. Licinio J. The tension between reductionistic and integrative approaches in molecular psychiatry. Molecular Psychiatry 1996;1:165-167.

263. Gold PW, Wong M-L, Chrousos GP, Licinio J. Stress system abnormalities in melancholic and atypical depression: molecular, pathophysiological, and therapeutic implications. Molecular Psychiatry 1996;1:257-264.

264. Licinio J. Molecular Psychiatry joins Biomedicine. Molecular Psychiatry 1996;1:345-346.

265. Licinio J. Molecular Psychiatry: One year of experience. Molecular Psychiatry 1996;1:419-420.

266. Licinio J. Molecular Psychiatry: does a new field need to examine strategy? Molecular Psychiatry 1997;2:3-5.

267. Licinio J. Biomedicine '98. Molecular Psychiatry 1997;2:429.

268. Licinio J. Leptin in anorexia nervosa and amenorrhea. Molecular Psychiatry 1997;2:267-269.

269. Licinio J, Gold PW, Chrousos GP, Sternberg EM. Forty years of neuroendocrinology: A tribute to SM McCann. Molecular Psychiatry 1997;2:347-349.

270. Licinio J, Gold PW, Chrousos GP, Sternberg EM. Forty years of neuroendocrinology: A tribute to SM McCann. Molecular Psychiatry 1997;2:347-349.

271. Licinio J. Molecular psychiatry at the millennium. Molecular Psychiatry 2000;5:1-2.

272. Licinio J. Farmacogenomica: oportunidades e desafios. Revista Brasileira de Psiquiatria 2001;23:122-123.

273. Licinio J. Inaugural editorial. The Pharmacogenomics Journal 2001:1.1-2.

274. Licinio J. Pharmacogenomics and ethnic minorities. The Pharmacogenomics Journal 2001:1:85.

275. Licinio J. New editorial policies: content and electronic submission. Molecular Psychiatry 2002;7:1.

276. Licinio J. Gene-environment interactions in Molecular Psychiatry. Molecular Psychiatry 2002;7:1123-124.

277. Licinio J. One year of The Pharmacogenomics Journal: content and electronic submissions. The Pharmacogenomics Journal 202:2.1.

278. Licinio J, Alvarado I. Progress in autism genetics. Molecular Psychiatry 2002; 7:229.

279. Licinio J, Alvarado I, Wong M-L. Autoimmunity in autism. Molecular Psychiatry 2002; 7:338.

280. Licinio J, Alvarado I, Wong M-L. Will pharmacogenomics guide clinical practice? The Pharmacogenomics Journal 2002:2.71.

281. Licinio J. Genomics brings psychiatry to a new era. The Economics of Neuroscience 2002;4:17.

282. Licinio J, Alvarado I, Wong ML. Patient-oriented investigation in pharmacogenomics. The Pharmacogenomics Journal 2002;2:137.
283. Licinio J, Alvarado I, Wong M-L. Conceptualizing depression. Molecular Psychiatry 2002;7:429.

284. Licinio J, Wong M-L. Brain-derived neurotrophic factor (BDNF) in stress and affective disorders. Molecular Psychiatry 2002;7:519.

285. Licinio J, Wong M-L. Complexity and pharmacogenomics. The Pharmacogenomics Journal 2002;2:203.

286. Licinio J, Yildiz B, Wong M-L. Depression and cardiovascular disease: co-occurrence or shared genetic substrates? Molecular Psychiatry 2002;7:1131-1132.

287. Licinio J, Wong M-L. Consent and pharmacogenomics. The Pharmacogenomics Journal 2002;2:343-344.

288. Licinio J, Wong ML. Sequence and function in pharmacogenomics. The Pharmacogenomics Journal 2003;3:123.

289. Licinio J, Wong ML. Approaches to dissecting mechanisms of adverse drug reactions in psychiatry: clozapine-binding sites in the bone marrow. The Pharmacogenomics Journal 2003;3:189.

290. Licinio J. Progress in psychiatric pharmacogenomics and new publication features. The Pharmacogenomics Journal 2003;3:249.

291. Licinio J. Pharmacogenomics and clinical medicine: passing flirtation or marriage? The Pharmacogenomics Journal 2003;3:303.

292. Licinio J. Lilly-Molecular Psychiatry Award: 2003 winners and 2004 call for submissions. Molecular Psychiatry 2003;8:567.

293. Licinio J, Wong M-L. Data from the Northern Finland 1966 Birth Cohort support an association between depression and immune function. Molecular Psychiatry 2003;8:711-712.

294. Licinio J, Wong M-L. The interface of obesity and depression: risk factors for the metabolic syndrome. Revista Brasileira de Psiquiatria 2003;25:196-197.

295. Licinio J. A leadership crisis in American psychiatry. Molecular Psychiatry 2004;9:1.

296. Licinio J, Wong M-L. Translational research in psychiatry: Pitfalls and opportunities for career development. Molecular Psychiatry 2004;9:117.

297. Licinio J, Wong M-L. Back to where it all started: monoamines and behavior – from drug responses to genes. Molecular Psychiatry 2004;9:427.

298. Licinio J. Ten years of Molecular Psychiatry. Molecular Psychiatry 2005;10:1-2.

299. Wong ML, Licinio J. Peripheral is central to the question. Molecular Psychiatry 2005;10:421-422.

300. Licinio J, Wong ML. Pharmacogenomics in psychiatry: clinical issues to be considered. Molecular Psychiatry 2005;10:615.

301. Licinio J, Wong ML. Pharmacogenomics in psychiatry: genomic considerations. Molecular Psychiatry 2005;10:713.

302. Licinio J. New directions for 2006. The Pharmacogenomics Journal. 2006;6:1.

303. Licinio J. Molecular Psychiatry: the highest Immediacy Index in the field of psychiatry. Molecular Psychiatry 2006;11:324

304. Llerena A, Licinio J. Hot topic: pharmacogenetic and pharmacogenomics. Current Drug Targets 2006;7:1639-1640.

305. Licinio J. Update on Molecular Psychiatry: new publication guidelines and new ways to stay current. Molecular Psychiatry 2009;14:463-464.

306. Licinio J. Potential diagnostic markers for postpartum depression point out to altered immune signaling. Molecular Psychiatry 2010;15:1.

307. Licinio J. Premier je suis, Second je fus, Molecular Psychiatry ne change. Molecular Psychiatry 2010;15:777.

308. Licinio J. The First International Conference on Translational Medicine. Molecular Psychiatry 2010;15:878–879.

309. Licinio J. Translational Psychiatry: leading the transition from the cesspool of devastation to a place where the grass is really greener. Translational Psychiatry (2011) 1, e1; doi:10.1038/tp.2011.3; published online 4 April 2011.

310. Licinio J, Wong M-L. Advances in depression research: 2011. Molecular Psychiatry 2011;16:686-687.

311. Licinio J, Wong M-Li. Why does the United States need a national centre for new cures? Molecular Psychiatry 2011;16:882-884.

312. Chrousos GP, Licinio J, Gold PW. In memoriam: Wylie Walker Vale, Jr. Molecular Psychiatry 2012;17:1052-1053.

313. Licinio J, Wong M-L. A novel conceptual framework for psychiatry: vertically and horizontally integrated approaches to redundancy and pleiotropism that co-exist with a classification of symptom clusters based on DSM-5. Molecular Psychiatry 2013;18:846-848.

314. Licinio J, Wong M-L. Launching the “War on Mental Illness.” Molecular Psychiatry 2014;19:1-5.

315. Licinio J, Wong M-L. Molecular Psychiatry: 20 Years. Molecular Psychiatry 2015;20:545–547.

316. Licinio J, Wong M-L. Molecular Psychiatry: Twenty years of progress from bench to clinic. Molecular Psychiatry 2015;20:657.

317. Licinio J, Wong M-L. Serotonergic neurons derived from induced pluripotent stem cells (iPSCs): A new pathway for research on the biology and pharmacology of major depression. Molecular Psychiatry 2016;21:1-2.

318. AW Licinio, Licinio J, Wong M-L. Biological and behavioural antidepressant treatment responses with the selective serotonin reuptake inhibitor fluoxetine can be determined by the environment. Molecular Psychiatry 2017;22:484.

1. Licinio J: Entering academic psychiatry: the resident's perspective. Presented at the workshop "Research Papers in Psychiatric Education," at the 1989 Midwinter Meeting of the American Association of Directors of Psychiatry Residency Training (AADPRT), San Diego, CA.

2. 05.11.1989 - Halmi KA, Licinio-Paixão J: Outcome: hospital program for eating disorders. Presented at the symposium "Eating Disorders, Treatment Strategies and Outcome," 142nd Annual Meeting of the American Psychiatric Association, San Francisco, CA.

3. 05.1990 - Licinio J (Chairman), Wong M-L, Franco H, Schlefer EK, Feltman D: Conducting research during clinical training: advantages and limitations. Presented as a workshop at the 143rd Annual Meeting of the American Psychiatric Association, New York, NY.

4. 09.27-29.1993 - Licinio J & Casper R (Rapporteurs): Study Group on Anorexia Nervosa (AN): Basic mechanisms, clinical approaches and treatment. Co-sponsored by AIREN (Association Internationalle pour la Recherche et l'enseignement en Neurosciences) and the World Health Organization, Geneva, Switzerland.

5. 09.21.1994 - "Expression of cytokines and their receptors in the central nervous system, with a focus on IL-1, IL-6, and IL-1 receptor antagonist," NIH Research Festival Workshop "Neuroimmune interactions: Focus on Cytokines and the Brain."

6. 09.20.1995 - Chairman. Workshop on “The use of chaos theory & biocomplexity in clinical research, a multidisciplinary approach.” NIH Research Festival.

7. 11.07.1995 - Chairman. NIH International Seminar “Use of non-linear dynamics and complexity measures in clinical research: relevance to molecular medicine.” Supported by the NIH, Office of the Director, Fogarty International Centre, and National Institute of Mental Health.

8. 12.15.1995 - Licinio J & Errol B. De Souza, Co-chairs, American College of Neuropsychopharmacology Panel. De Souza EB, Licinio J, Weiss J, Campbell IL, Vitkovic L: Novel developments in the neurobiology of cytokines: Pathophysiological implications. San Juan, Puerto Rico.

9. 03.09.1996 - Licinio J: Cytokines and central nervous systems functions. Presented at the Alpha Interferon Symptom Management Consensus Conference, sponsored by the Cancer Treatment Evaluation Program at the National Cancer Institute and University of Maryland Cancer Centre, Baltimore, MD, 03.08-10.1996.

10. 05.08.1996 - Licinio J, Chairman, A.P.A. symposium: The neurobiology of cytokines. Presented at the 149th Annual Meeting of the American Psychiatric Association, New York, NY.

11. 06.16.1996 - Licinio J: Chairperson, session: Neuroimmunoendocrinology, Third Advanced Rheumatology Conference, São Paulo Rheumatology Society, São Paulo, Brazil.

12. 11.16.1996 - Licinio J: Hormones and the brain. Presented at the Science Symposium sponsored by the Institute for Advanced Studies in Immunology and Aging, a World Health Organization Collaborating Centre for Aging and Health, Georgetown University, Washington, DC.

13. 04.26.1997 - Chairman, Biomedicine ‘98 Theme Symposium “Medically relevant advances in molecular psychiatry.” Washington, D.C.

14. 03.22-25.1997 - Licinio J, Discussant - European Union Meeting: Viruses and Disorders of the Brain. Queens' College, Cambridge, UK.

15. 05.02.1998 - Chairman, Biomedicine ‘98 ThemTheme Symposium “Advances in Molecular Psychiatry/Neuroscience.” Washington, D.C.

16. 07.15.1998 - Round Table Discussant: "Bringing neuroimmunology from the bench to the clinic. 1998 FASEB Summer Conference: "Neural-Immune Interactions in Injury and Disease: Pathways to Therapy."

17. 06.26.1998 - Chairman, Oral Session: Basic Science of Obesity. 1998 Annual Meeting of the Endocrine Society, New Orleans, LA.

18. 09.06.1998 - Licinio J: "Hormones and emotions." Presented at the University of São Paulo School of Medicine, Institute of Psychiatry Symposium "Mood Regulation," Araxa, MG, Brazil.

19. 09.13.1998 - Chairman, Oral Session: "Cells And Tissues." 13th International Conference on Comparative Physiology - Aging in animals and humans: from cell to organism. Troina (Sicily), Italy.

20. 04.18.1999 - Chairman, American Federation for Medical Research 1999 Annual Meeting at

Experimental Biology '99 Theme Symposium "Translational Research in Psychiatry: From Molecular Medicine to Clinical Practice.” Washington, D.C.

21. 12.14.1999 - Julio Licinio & Husseni Manji, co-chairs, American College of Neuropsychopharmacology Panel “Translational research in pharmacogenetics and pharmacogenomics.” Acapulco, Mexico.

22. 01.22.2000 - Chairman, Session “Psychoneuroimmunology of Alzheimer’s disease.” Expert Meeting on Psychoneuroimmunology, Innsbruck, Austria.

23. 10.12.2000 - Chairman, Session “Introduction: Paving the Way to Pharmacogenomics.” Pasteur Institute Euroconference “Pharmacogenetics and Pharmacogenomics,” Paris, France.

24. 10.13.2000 - Chairman, Session “Pharmacogenomics: Studies in Common Diseases.” Pasteur Institute Euroconference “Pharmacogenetics and Pharmacogenomics,” Paris, France.

25. 05.24.2001 – Moderator, Online discussion session “Pharmacogenomics,” hosted by Bioonline (www.bio.com)

26. 06.30.2001 – Chairman, Session “Psychoneuroimmunology of Schizophrenia.” VIII Expert Meeting in Psychoneuroimmunology, Münster, Germany.

27. 10.11.2001 – Chairman, Session “Metabolism/Targets” at the Meeting, Pharmacogenomics: The Molecular Prescription Pad. Cambridge, MA.

28. 10.29.2001 – Panelist, session “Innovative Methods for Recruiting and Educating the Public,” The National Human Genome Research Institute and The Pew Charitable Trusts Public Engagement and Education Meeting, National Institutes of Health, Bethesda, MD.

29. 10.17.2002 – Co-chair, Session “Advances in Genomics of CNS Diseases.” Institut Pasteur Euroconference co-sponsored by the New England Journal of Medicine “Pharmacogenomics: The Promise and Reality of Individualized Treatment,” Paris, France.

30. 04.02.2003 – Chair, Session “Oral Presentations IA,” 2003 Annual Meeting of the American Society of Clinical Pharmacology and Therapeutics, Washington, DC.

31. 06.28.2004 – Presenter, “NIH K Awards,” at the Workshop “Success in Academia,” organized by the UCLA Centre on Research, Education, Training and Strategic Communications on Minority Health, Los Angeles, CA.

32. 05.21.2005 – Chair (Charles Nemeroff, co-chair), Symposium “New Insights on Unipolar Depression: Therapeutic Implications,” 2005 Annual Meeting of the Society for Biological Psychiatry.

33. 12.13.2007 – Chair and Discussant (Ma-Li Wong, co-chair), Panel “Whole Genome Association (WGA) Studies in Psychiatry: Opportunities and Pitfalls,” 2007 Annual Meeting of the American College of Neuropsychopharmacology.

34. 11.14.2009 – Symposium Chair: Immune Cell and Antibody Alterations, 10th Psychoimmunology Expert Meeting Symposium: Immune/Brain Cell Systems & Infectious Agents, Science Conference Centre “Schloss Reisensburg“ of Ulm University, Germany.

35. 12.01.2009 – Panel Member: Public Lecture: Antidepressants: Friend or Foe. 2009 Annual Meeting of the Australian Society for Psychiatric Research, Canberra, Australia.

36. 12.03.2009 – Chair: Early Career Researcher Colloquium. 2009 Annual Meeting of the Australian Society for Psychiatric Research, Canberra, Australia.

37. 05.25.2010 – Symposium Chair: Translating Genomics to Healthcare: The Pharmacogenomics of Depression. 56th Annual Meeting of the Society of Biological Psychiatry, New Orleans, Louisiana.

38. 05.25.2010 – Leader: Small Interactive Session. How to get your paper published. 2010 Annual Meeting of the American Psychiatric Association, New Orleans, Louisiana.

39. 05.24.2010 – Invited Symposium Chair: Depression, Metabolic Syndrome and Obesity. 2010 Annual Meeting of the American Psychiatric Association, New Orleans, Louisiana.

40. 05.25.2010 – Presidential Symposium Co-chair: Recent Advances in Psychiatric Genetics: From Fundamental Discovery to Clinical Implications. 2010 Annual Meeting of the American Psychiatric Association, New Orleans, Louisiana.

41. 06.19.2010 – Presenter, “ Vision for Translational Research” at the Trauma & Orthopedic Research Unit Retreat, ANU, Kioloa Campus, NSW, Australia.

42. 08.16.2010 – Chair and Organizer: John Curtin School of Medical Research Symposium: New Perspectives in "Clinical Neuroscience and Mental Health, Canberra, Australia.

43. 08.17-20.2010 – Chair and Organizer, Bootes Course on Translational Medicine: "The Pathway from Discovery to Healthcare," John Curtin School of Medical Research, Australian National University, Canberra, Australia.

44. 08.30.2010 – Chair and Organizer, Translational Research on the Brain:" Accelerating the Pathway from Discovery to Healthcare – First Annual National Conference at The John Curtin School of Medical Research, Australian National University, Canberra, Australia.

45. 11.1-4.2010 – Chair and Organizer, First International Conference on Translational Medicine, The 13th Frank and Bobbie Fenner Conference, John Curtin School of Medical Research, Australian National University, Canberra, Australia.

46. 04.4-5.2011 – Chair and Organizer, First National Symposium on Translational Psychiatry, The John Curtin School of Medical Research, Australian National University, Canberra.

47. 04.4.2011 – Co-chair, Round Table Panel Discussion: "The Future of Scientific Publishing: When to go to new venues, when to stick to traditional journals, First National Symposium on Translational Psychiatry, The John Curtin School of Medical Research, Australian National University, Canberra.

48. 12.07.2011 – Chair, Neural stem cells and neurodegeneration session at the DisCUSS meeting on Stem Cells, Dresden, Germany.

49. 12.01.2011 – Member of concluding panel, 75th Anniversary Symposium of the National Health & Medical Research Council, Canberra, Australia.

50. 05.19.2013 – Chair, American Psychiatrion Association 2013 Meeting Frontiers of Science session honoring Nobel Laureate Andrew Schally: “Beneficial Effects of novel antagonists of GHRH in different models of Alzheimer’s disease,” San Francisco, California, USA.

51. 05.19.2013 – Chair, American Psychiatrion Association 2013 Meeting Frontiers of Science session honoring Professor Jan-Ake Gustafsson: “ERB and LXRB in CNS,” San Francisco, USA.

52. 08-89.2013 – Conference Organizer and Chair – Second National Symposium on Translational Psychiatry, Adelaide, Australia.

53. 06.27.2014 – Conference Organizer and Chair – South Australian Health and Medical Research Institute (SAHMRI) Translational Neuroscience Day and Inaugural Samuel Gershon Medal for Lifetime Achievement in Translational Neuroscience (awarded to Professor Samuel Berkovic, University of Melbourne).

54. 05.18.2015 – Chair of the session: A preview of breaking new research on adolescent drinking, schizophrenia and suicide from the American Journal of Psychiatry and Molecular Psychiatry. Annual Meeting of the American Psychiatric Association, Toronto, Canada.

55. 05.19.2015 – Moderator of the Advances in Medicine session: Cancer control in the 21st Century – Challenges and opportunities. Annual Meeting of the American Psychiatric Association, Toronto, Canada.

56. 05.20.2015 – Moderator of the Scientific and Clinical Reports session: Mood Disorders. Annual Meeting of the American Psychiatric Association, Toronto, Canada.

57. 10.26.2015 – Session Chair: Surveying large cohorts, SAHMRI 2015 Scientific Symposium “Big Data,” Adelaide, South Australia.

58. 10.31.2015 – Session Co-Chair (with Andres Buonanno, NIH): Working towards translational models for endophenotypes in psychiatric disorders. Molecular Psychiatry Meeting, San Francisco, California.

59. 11.19.2015 – The Future of Psychiatry, Young Psychiatrists Workshop II: Meeting Professor Dinesh Bhugra & Professor Julio Licinio. International Congress of the World Psychiatric Association, Taipei, Taiwan.

60. 11.21.2015 – Symposium Chair: Neuroimaging Studies on Attention-Deficit Hyperactivity Disorder. International Congress of the World Psychiatric Association, Taipei, Taiwan.

61. 05.14.2016 – Symposium Co-chair (wih Alexander Niculescu, University of Indiana): Precision Medicine in Psychiatry: Found, Not Lost, in Translation. 71st Annual Meeting of the Society of Biological Psychiatry, Atlanta, Georgia, USA.

62. 05.16.2016 – Session Chair. APA Frontiers of Science Lecture Series: Thinking differently about mental illness and gun violence: Balancing risk and rights for effective policy. Presented by Jeff O. Swanson at the 169th Annual Meeting of the American Psychiatric Association, Atlanta, Georgia, USA, 05.16.2016.

63. 05.27.2016 – Session Chair. The brain and mental health: Increasing awareness and decreasing stigma. 2016 Brain Forum, Lausanne, Switzerland.

1. 12.10.1987 – “Eating Disorders,” Department of Psychology, Barnard College of Columbia University, New York, New York.

2. 03.01.1988 – “Insulin Secretion and the Regulation of Appetite,” Department of Physiology, Health Sciences Institute, Federal University of Bahia, Brazil.

3. 03.04.1988 – “Psychoendocrinology of Anorexia Nervosa,” Hospital Juliano Moreira, Department of Psychiatry, Federal University of Bahia, Brazil.

4. 05.12.1989 – “Studying Endogenous Instantaneous Hormonal Secretion Rates in Psychiatric Patients: Advantages and Limitations,” Westchester Division Research Seminar, The New York Hospital-Cornell University Medical Centre.

5. 03.14.1989 – “Techniques to Assess Instantaneous Insulin Secretion Rates in Eating Disorders: Implications for the Study of the Regulation of Food Intake and Body Weight,” Eating Disorders Program, The New York Hospital-Cornell University Medical Centre, Westchester Division.

6. 11.29.1989 – “Treatment of Eating Disorders.” Department of Human Nutrition and Food Systems, University of Maryland, College Park, Maryland

7. 12.06.1989 – “Use of Mathematical Modelling in Psychiatric Research.” Presented at St. Louis University School of Medicine, Department of Psychiatry Grand Rounds.

8. 02.13.1990 – “Methods to Assess Hypothalamic-pituitary-adrenal Function in Patients with the Tryptophan-associated Eosinophilia Myalgia Syndrome (EMS),” Presented at the joint EMS Conference, National Institute of Arthritis and Musculoskeletal and Skin Diseases/National Institute of Mental Health, NIH, Bethesda, Maryland.

9. 04.12.1990 – “Endocrinology of Anorexia Nervosa.” Presented to the Department of Psychology, University of Maryland, College Park, Maryland.

10. 04.27.1990 – “The Role of CRH in the Susceptibility to Depressive and Inflammatory Disorders.” Presented at Albert Einstein College of Medicine (Bronx, NY), Department of Psychiatry Grand Rounds.

11. 05.05.1990 – “Insulin in Eating Disorders.” Presented at the Columbia University College of Physicians & Surgeons Appetitive Seminar Series, New York, NY.

12. 06.13.1990 – “Medical Complications of Eating Disorders.” Department of Psychiatry, Georgetown University School of Medicine, Washington, D.C.

13. 02.21.1992 – “Neurobiology of Cytokines.” Works-in-Progress Seminar, Department of Psychiatry, Yale University School of Medicine, WHVAMC, West Haven, CT.

14. 03.24.1993 – “The Neurobiology of Cytokines: From Molecular Biology to Clinical Psychiatry.” Research Seminar, Department of Psychiatry, The University of Chicago, Pritzker School of Medicine, Chicago, IL.

15. 03.26.1993 – “Assessing Circulating Levels of Cytokines.” Works-in-Progress Seminar, Department of Psychiatry, Yale School of Medicine, WHVAMC, West Haven, CT

16. 03.30.1993 – “The Neurobiology of Cytokines: From Molecular Biology to Clinical Psychiatry.” Grand Rounds, Department of Psychiatry, The University of Texas Medical Branch, Galveston, TX.

17. 04.13.1993 – "The Neurobiology of Cytokines." Research Seminar, Department of Psychiatry, The University of Michigan, Ann Arbor, MI.

18. 09.28.1993 – “The Hypothalamic-pituitary-adrenal Axis in Anorexia Nervosa.” Study Group on Anorexia Nervosa: Basic Mechanisms, Clinical Approaches and Treatment. Cosponsored by AIREN-Association Internationalle pour la Recherche et l'enseignement en Neurosciences and the World Health Organization, Gèneve, Switzerland.

19. 11.17.1993 – “The Neurobiology of Cytokines” Seminar, Clinical Neuroendocrinology Branch, NIMH, NIH, Bethesda, MD.

20. 02.20.1994 – “Biological Aspects of Eating Disorders.” Joint Seminar, Departments of Psychiary and Medicine, Federal University of Bahia School of Medicine, Salvador, Bahia, Brazil.

21. 03.29.1994 – “Localization of Cytokine and Cytokine Receptor mRNA in Rat Brain.” Seminar, Division of Cytokine Biology, Centre for Biological Evaluations and Research, Food and Drug Administration, DHHS, Bethesda, MD.

22. 06.09.1994 – “Localization of IL-1 and IL-1 Receptor Antagonist mRNA in Rat Brain.” NIH-wide Neural-Immune Interest Group Seminar. NIH, Bethesda, MD 20892.

23. 01.25.1995 – “Localization of Cytokines and Cytokine Receptors in Brain.” NIH Clinical Centre Grand Rounds, NIH, Bethesda, MD 20892.

24. 10.28.1995 – “The Role of Stress in the Susceptibility to Inflammatory Disease.” UCLA Symposium – Beyond Mood: Brain Mechanisms in Stress and Disease, Los Angeles, CA.

25. 04.25.1996 – “The Neurobiology of IL-1 Receptor Antagonist: Induction by Inflammatory Mediators.” French Association of Neuropsychopharmacology Meeting – Neuropathology of Brain Cytokines. St. Jean de Luz, France

26. 06.14.1996 – “The Endogenous Interleukin 1 Receptor Antagonist: Molecular Biology, Physiology, and Relevance in Pathophysiology of Arthritis and Brain Disorders.” Third Advanced Rheumatology Conference, São Paulo Rheumatology Society, São Paulo, Brazil.

27. 06.16.1996 – “Stress and Immune Function: Clinical implications of Neuroendocrine-Neuroimmune Interactions in Arthritis and Depression.” Third Advanced Rheumatology Conference, São Paulo Rheumatology Society, São Paulo, Brazil.

28. 06.20.1996 – “Neuroendocrinology of Depression.” Second symposium on Advances in Neurosciences in the Decade of the Brain, sponsored by the Unit on Neuroscience, Division of Mental Health, WHO, Collegium Internationale Neuro-Psychopharmacologicum (C.I.N.P.), and Department of International Cooperation, Ministry of Health, Beijing, China.

29. 11.14.1996 – “The Gene Encoding For The Novel Transacting Factor Proopiomelanocortin Corticotropin-Releasing Hormone Responsive Element Binding Protein 1 (PCRH-REB-1) is Constitutively Expressed in Rat Pituitary and in Discrete Brain Regions Containing CRH or CRH Receptors: Pathophysiological Implications.” Third International Congress of Neuroimmunomodulation, Bethesda, MD

30. 11.19.1996 – “State of the Art: Psychoneuroendocrinology.” Plenary Lecture at the 22nd Brazilian Congress of Endocrinology and Metabolism, Salvador, Bahia, Brazil.

31. 11.21.1996 – “Melatonin: Myth or Reality.” Plenary Lecture at the 22nd Brazilian Congress of Endocrinology and Metabolism, Salvador, Bahia, Brazil.

32. 11.21.1996 – “Meet the Professor: Anorexia Nervosa and Bulimia,” 22nd Brazilian Congress of Endocrinology and Metabolism, Salvador, Bahia, Brazil.

33. 11.29.1996 – “The Biology and Psychology of Depression,” presented at the 11th International Conference ‘In the Image and Likeness of God: Always? The Mental Ailments,’ sponsored by Fiorenzo Cardinal Angelini and the Pontifical Council for Pastoral Assistance to Health Care Workers, and attended by Pope John Paul II, Paul VI Auditorium, Vatican City (Nature Medicine 1997; 3: 7).

34. 12.04.1996 – “Psychoneuroimmunology: Clinical Implications.” State of New York Office of Mental Health Research Conference, Albany, New York.

35. 03.04.1997 – “Inducible Nitric Oxide Synthase and Cytokine Gene Expression in the Central Nervous System: Pathophysiological Relevance.” NIH NGF Club, Bethesda, MD

36. 06.25.1997 – “Advances in Psychoneuroimmunology Research at NIH.” Psychiatric Nursing Internship Program, Warren Grant Magnuson Clinical Centre, National Institutes of Health, Bethesda, MD

37. 10.22.1997 – “Human Leptin Levels and Endocrine Function.” NIH Clinical Centre Grand Rounds, sponsored by the NIH-wide Clinical Research Special Interest Group.

38. 12.05.1997 – “Pathways and Mechanisms of Cytokine Signaling of the Central Nervous System.” Endocrine Grand Rounds, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.

39. 02.11.1998 – “Neuroendocrine-immune Interactions: Mechanisms and Pathways.” Research Seminar, Department of Biochemistry and Molecular Pharmacology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA

40. 02.16.1998 – “The Endocrine Effects of Leptin.” Research Seminar, Department of Nutrition, University of Milano, Milano, Italy.

41. 02.25.1998 – “Brain Responses in Systemic Illness: Molecular Mechanisms and Clinical Implications.” Grand Rounds, Department of Psychiatry, Northwestern University, Chicago, IL.

42. 03.19.1998 - “Leptin, Hypothalamic Function, and Behavior.” Grand Rounds, Department of Psychiatry, University of Maryland Medical Centre, Baltimore, MD.

43. 06.18.1998 – “Pathways and Mechanisms of Cytokine Signalling of the Central Nervous System.” Research Seminar, University of California, Los Angeles.

44. 09.02.1998 – “The Neuroendocrinology of Depression: Progress and New Opportunities.” Grand Rounds at the Institute of Psychiatry of the Universiy of São Paulo School of Medicine, São Paulo, SP, Brazil.

45. 09.03.1998 – “The Neuroendocrinology of Leptin.” Graduate Research Seminar, Departments of Physiology and Pharmacology, Federal Universiy of Minas Gerais Health Sciences Institute, Belo Horizonte, MG, Brazil.

46. 10.5.1998 – “Novel Approaches to Clinical Research in Depression: From Molecular Biology to Clinical Neuroendocrinology.” Research Seminar, Medical College of Wisconsin, Milwaukee, WI.

47. 01.18.1999 – “Research Strategies in Depression: Study of Candidate Systems and the Search for Novel Genetic Targets." DIBIT- San Raffaele Hosptal, Milano, Italy.

48. 01.20.1999 – “Mechanisms and Pathways of Cytokine Signaling of the Central Nervous System.” Jacques Monod Amphiteatre, Department of Pathophysiology, Pasteur Institute, Paris, France.

49. 02.23.1999 – “Neuroendocrinology of Depression: Candidate Systems and the Search for New Genes.” Psychiatry Grand Rounds, University of Southern California, Los Angeles, CA.

50. 08.03.1999 – “Research Strategies in Depression: Examination of Candidate Systems and the Search for New Mechanisms.” Grand Rounds, Department of Psychiatry, State University of New York, Health Sciences Centre at Syracuse, Syracuse, New York.

51. 08.28.1999 – “The Neuroimmune-endocrine Axis: Pathophysiological implications of CNS Cytokines and HPA Hormones Dynamics.” Plenary lecture at the 1999 Annual Meeting of the Brazilian Federation of Societies of Experimental Biology, Brazilian Society of Physiology, Caxambu, MG, Brazil.

52. 09.01.1999 – “The Neuroimmune-endocrine Axis: Pathophysiological implications of CNS Cytokines and HPA Hormones Dynamics.” First International Meeting on Adrenal Diseases - Basic and Clinical Aspects. Ribeirão Preto, SP, Brazil.

53. 02.08.2000 – “Depression, Stress, and Atherosclerosis: Potential mechanisms.” Presented to the Division of Cardiology, Department of Medicine, UCLA Health Sciences Centre, Los Angeles, CA.

54. 02.15.2000 – “Neuroendocrine and Pharmacogenomic Approaches to the Biology of Depression.” Grand Rounds, Department of Psychiatry, University of Chicago, Chicago, IL.

55. 05.24.00 – “Neurobiology of Inflammatory Mediators: Clinical Implications.” Seminars in Clinical Research Rockefeller University Hospital, New York, NY

56. 06.23.2000 – “Pharmacogenetics of Antidepressants in Mexican-Americans.” Research Seminar, Mayo Clinic, Rochester, MN.

57. 07.13.2000 - “Endocrine Effects of Human Leptin.” Grand Rounds, Pennington Biomedical Research Centre, Louisiana State University, Baton Rouge, LA.

58. 07.20.00 – “Pharmacogenetics.” Lecture at the UCLA GCRC Course, The Essentials of Clinical Investigation: Developing a Research Proposal.

59. 08.18.2000 – “Pharmacogenetics and Pharmacogenomics of Antidepressant Treatment.” Neuroscience Seminar, Merck Research, West Point, PA.

60. 09.18.2000 – “Pharmacogenetics: New Directions and Clinical Implications.” Grand Rounds, Daniel Freeman Memorial Hospital, Inglewood, CA.

61. 09.19.2000 – “Depression in the 21st Century: Conventional Approaches and New Opportunities.” Grand Rounds, Maine Medical Centre (University of Vermont ), Portland, Maine.

62. 11.01.2000 – “Emerging Opportunities for Translational Research in Psychiatry.” Grand Rounds, Baylor College of Medicine (Texas Medical Centre), Department of Psychiatry Houston, Texas.

63. 12.06.2000 – “Leptin, Depression, and Endocrine Systems,” Grand Rounds, UCLA Division of Endocrinology, diabetes, and hypertension. UCLA Health Sciences Centre, Los Angeles, CA.

64. 01.30.2001 – “Emerging Opportunities for Translational Research in Psychiatry.” Grand Rounds, University of Alabama School of Medicine, Department of Psychiatry, Birmingham, Alabama.

65. 02.15.2001 – “Emerging Opportunities for Translational Research in Psychiatry.” Grand Rounds, University of Tennessee School of Medicine, Department of Psychiatry, Memphis, Tennessee.

66. 05.15.2001 – “Psychoneuroendocrinology” – Lecture to PGY-4 Psychiatry Residents, UCLANPI/H.

67. 06.13.2001 – “Scientific publications in high impact journals: The editor’s perspective.” Seminar at the Federal University of São Paulo School of Medicine, São Paulo, SP, Brazil.

68. 07.02.2001 – “Cytokines and the neuroendocrine-stress axis involved in infection vulnerability of the brain.” Neurovirology Colloquium, Robert Koch-Institut, Berlin, Germany.

69. 07.19.2001 – “Pharmacogenetics.” Lecture at the UCLA GCRC Course, The Essentials of Clinical Investigation: Developing a Research Proposal.

70. 07.20.2001 – “How to Prepare a Scientific Presentation.” Lecture at the UCLA GCRC Course, The Essentials of Clinical Investigation: Developing a Research Proposal.

71. 08.03.2001 - Primary Care College Foundations Week, Clinical Pharmacology Lecture for third year medical students and group moderator, UCLA School of Medicine.

72. 10.26.2001 – “Depression: Molecular Mechanisms and Pathways Underlying Candidate Systems and Pharmacogenomic Approaches to Identify Novel Targets. Research Seminar presented to the Department of Psychiatry & Human Behavior, University of California, Irvine, College of Medicine.

73. 05.07.2002 – “Pharmacogenetics: The Paradigm of Psychopharmacology.” Grand Rounds, Lilly Research Laboratories, Indianapolis, Indiana.

74. 02.21.2003 – “Inflammation, Stress, and Disease Susceptibility: Translational Studies in Common and Complex Disorders.” Presentation to the Graduate School, Yonsei University, Seoul, Korea.

75. 04.03.2003 – “Dissecting a complex phenotype: leptin and obesity.” Seminar presented at the Clinical Neuroendocrinology Branch, NIMH Intramural Research Program, NIH, Bethesda, Maryland.

76. 07.09.2003 – “Dissecting a complex phenotype: leptin and obesity.” Seminar presented at the NIH Director’s Conference Room, sponsored by the Director, National Institute of Mental Health, NIH, Bethesda, Maryland.

77. 08.22.2003 – “Pharmacogenomic approaches to the study of complex phenotypes: obesity and depression.” Seminar presented at the Fiocruz Foundation, Salvador, Bahia, Brazil

78. 09.15.2003 – “Pharmacogenomic approaches to complex phenotypes: depression and obesity.” Seminar presented at the Department of Psychiatry, University of Texas Health Sciences Centre San Antonio.

79. 11.13.2003 – “Treatment based on genetic profiles: From promise to reality.” Presented at the David Geffen School of Medicine at UCLA, Board of Visitors Meeting, Los Angeles.

80. 11.14.2004 – “New directions on obesity research.” Presented at the National Institute of Diabetes, Digestive, and Kidney Diseases, NIH Clinical Centre, Bethesda, Maryland.

81. 03.16.2005 – “Depression, Antidepressants, and Suicidality: A Critical Appraisal” and “Suicide in the U.S. 1960-2002: Impact of Fluoxetine Prescriptions.” Presented at Lilly Research Laboratory, Indianapolis, Indiana.

82. 07.14.2005 – “Pharmacogenomic approaches to common and complex disorders.” Presented at the University of Dresden School of Medicine, Germany.

83. 08.10.2005 – “Update on common and complex disorders: Hormones and behavior – obesity and leptin; depression and CRH.” Presented to the State of Bahia Endocrine Society, Hospital Aliança, Salvador, Bahia, Brazil.

84. 05.05.2007 – "Genomics & Pharmacogenomics in Psychiatry." Presented at Future Leaders in Psychiatry, Atlanta, GA.

85. 05.12.2007 – "Depression as a Neuroimmune Disorder." Presented at The New York Neuropsychology Group, New York, NY.

86. 07.26.2007 – "Pharmacogenomics of Depression." Presented at the Collaborative Seminar Series-Scripps Research Institute, Jupiter, FL.

87. 09.14.2007 – "Replacement Treatment of Genetically Based Leptin Deficiency." Presented at the Grand Rounds at Mt Sinai Medical Centre, Miami, FL.

88. 09.17.2007 – "The Promise of Translational Science." Presented at the Foundations of Translational Research Training, Miami, FL.

89. 02.22.2008 – "Pharmacogenomics of Depression and Obesity." Presented at the University of Miami, Department of Psychiatry, Samuel Gershon Teaching Awards, Miami, FL.

90. 03.08.2008 – "The Pharmacogenetics of Antidepressant Treatment Response." Presented at the University of Miami 2008 Medical Alumni Weekend, Miami, FL.

91. 04.02.2008 – "Pharmacogenetics of Obesity & Depression: From Single-molecule Based Treatments of Monogenetic Disease to Multigenic Impact Treatment Response in Common Disorders." Presented at Ste. Anne Hospital, Paris, France.

92. 04.22.2009 – “Pharmacogenomics of Obesity and Depression: From single-molecule based treatments of monogenetic disease to multigenic impact on treatment response in common and complex disorders.” Seminar presented at the John Curtin School of Medical Research, Australian National University, Canberra, Australia.

93. 04.24.2009 – “Pharmacogenomics of Obesity and Depression: From single-molecule based treatments of monogenetic disease to multigenic impact on treatment response in common and complex disorders.” Seminar presented at the Duke-NUS, Graduate Medical School, Singapore.

94. 11.26.2009 – “Depression and Obesity: What to do When one Feels Sad & Fat” Presented at the ANU Wellbeing Week, session: Chronic Disease & Depression, Canberra, Australia.

95. 03.10.2010 – “Approaches to Pharmocogenomics: The Cases of Monogenetic and Polygenic Diseases.” Presented at the Queensland Brain Institute Seminar Series, Brisbane, Australia.

96. 04.27.2010 – “Translational research in obesity: lessons from genetically-based leptin deficiency.” Presented as a University of Melbourne Seminar, Melbourne, Australia.

97. 06.22.2010 – “Leptin and Genetic Obesity: From bench to bedside and back to the bench.” ANU Medical School Dean’s Lecture at The Canberra Hospital.

98. 07.29.2010 – “Translational Research in Obesity and Depression: Approaches to Monogenetic and Common and Complex Diseases.” Presented as a Queensland Institute of Medical Research Seminar.

99. 08.10.2010 – “Translational Research in Obesity and Depression: Approaches to Monogenetic and Common and Complex Diseases.” Presented at ANU Cutting Edge, Burton & Garran Hall, Canberra.

100. 08.17.2010 – “Overview of Translational Medicine.” Presented at the Bootes Course on Translational Medicine: The Pathway from Discovery to Healthcare," John Curtin School of Medical Research, Australian National University.

101. 08.20.2010 – “Summary and Conclusions – Translational Medicine.” Presented at the Bootes Course on Translational Medicine: "The Pathway from Discovery to Healthcare," John Curtin School of Medical Research, Australian National University.

102. 09.19.2008 – “Pharmacogenetics of Obesity & Depression.” Presented at the 3er Diplomado en Investigación Genómica, La Universidad Autónoma de la Ciudad de México y el Instituto de Ciencia e Tecnologia del Distrito Federal, Mexico City, Mexico.

103. 09.06.2010 – “Advances in Depression Research.” Presented at FLENI: Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires, Argentina.

104. 09.07.2010 – “From bench to clinical care: Pharmacogenomics of obesity and depression.” Presented at the University of Buenos Aires School of Medicine, Buenos Aires, Argentina.

105. 09.08.2010 – “Pharmacogenetics of Depression.” Presented at the Department of Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

106. 09.09.2010 – “Pharmacogenomics of obesity.” Presented at the Department of Genetics, Federal University of Rio Grande do Sul, Porto Alegra, RS, Brazil.

107. 09.29.2010 – “The role of the adipokine leptin throughout the life span.” Paediatric Grand Rounds, The Canberra Hospital, Australia.

108. 10.27.2010 – “Translational dissection of phenotypes into monogenetic versus common and complex: The case of obesity and depression.” Presented at the Mental Health Research Institute and University of Melbourne, Australia.

109. 03.25.2011 – “A sneak peak at the psychiatry of the future.” Presented at Orygen Youth Health Research Centre, University of Melbourne, Australia.

110. 03.30.2011 – “A missense leptin gene mutation: from rare disease to insights into biology and therapeutics.” Presented (via videolink) at the Workshop Frontiers in Molecular Biology and Biotechnology, Islamabad, Pakistan.

111. 05.10.11 – “Personalising antidepressant treatment.” Presented at the Black Dog Institute, Sydney, NSW, Australia.

112. 07.26.2011 – “Pharmacogenomics of obesity and depression.” Presented at the Department of Neuroscience, Physiology and Pharmacology, University College, Gower Street, London, U.K.

113. 07.29.2011 – “Obesity and Depression. Shared Mechanisms.” Presented at the Australian National University Counseling Centre Symposium, Canberra.

114. 08.12.2011 – “A sneak peak at the psychiatry of the future.” Brain & Mind Research Institute, University of Sydney, Seminar.

115. 08.18.2011 – “Translational research in obesity.” Lecture at course BIOL3190, Australian National University Medical School, Canberra.

116. 08.26.2011 – “A missense leptin gene mutation: from rare disease to insights into biology and therapeutics.” University of Western Sydney School of Medicine Research Colloquium.

117. 08.27.2011 – “Obesity and Depression. Shared Mechanisms.” Presented at the Open Day, John Curtin School of Medical Research, Australian National University, Canberra.

118. 11.09.2011 – “From rare mutation to common disease: leptin and obesity.” Lecture at University House, Australian National University, Canberra, Australia.

119. 11.30.2011 – “From bench to clinic: Antidepressant-induced weight gain.” Lecture at the 75th Anniversary Symposium of the National Health & Medical Research Council, Canberra, Australia.

120. 12.12.2011 – “Re-conceptualizing depression: What are today’s most promising research leads? Where will the next breakthroughs come from?” Lecture at the Institute of Psychiatry, King’s College, London, U.K.

121. 12.13.2011 – “Publishing in high impact psychiatry journals: An editor’s insight.” Lecture at the Institute of Psychiatry, King’s College, London, U.K.

122. 04.10.2012 – “Publishing in high impact journals: An editor’s insight.” Seminar at the University of Göttingen Medical School, Germany.

123. 04.16.2012 – “Publishing in high impact journals: An editor’s insight.” Seminar at the Santa Maria's Hospital, University of Lisbon Medical School, Lisbon, Portugal.

124. 04.16.2012 – “Translational Science of Depression: New Perspectives.” Seminar at the Egas Moniz Molecular Medicine Institute, University of Lisbon, Lisbon, Portugal.

125. 04.20.2012 – “Translational Science of Academic Medicine: Depression, Obesity and their Interface as Case Examples.” Seminar at the Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.

126. 12.06.2012 – “Depression, obesity, and their interface: Translational approaches,” Seminar at the Queensland Institute of Medical Research.

127. 06.18.2012 – “Depression, obesity and their interface,” Seminar at the Department of Physiology, Monash University, Melbourne.

128. 07.17.2012 – “Depression, obesity and their interface.” Seminar at the Division of Endocrinology, National University of Singapore.

129. 07.17.2012 – “Depression, obesity and their interface.” Seminar at the Division of Endocrinology, National University of Singapore.

130. 07.19.2012 – “Translational Research: Obesity, depression and their interface as case examples.” Department of Medicine Grand Rounds, National University of Singapore.

131. 08.07.2012 – “Developing and applying the science of translational medicine: Stress, depression, obesity and their interface. Seminar at the Uniformed Services University of the Health Sciences, Bethesda, Maryland.

132. 08.13.2012 – “Developing and applying the science of translational medicine: Stress, depression, obesity and their interface.” Seminar at Georgia Health Sciences University, Augusta, Georgia.

133. 10.26.2012 – “Translational research applied to psychiatry and neuroscience: A new paradigm applied to depression.” Seminar at the INSERM Centre for Psychiatry and Neuroscience, University of Paris-Descartes and Hospital Sainte-Anne, Paris, France

134. 8.8.2013 – “The paradox of psychiatry in 2013.” Keynote lecture at the opening of the Second National Symposium on Translational Psychiatry and launch of the Mind-Brain Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.

135. 7.10.2014 – “Depression, obesity and their interface.” Invited lecture at the Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

136. 7.29.2014 – “Demystifying mental illness: What is depression?” Invited Lecture at the Commonwealth Club, Adelaide, Australia.

137. 07.29.2014 – “Demystifying mental illness: What is depression?” Invited Lippman Fellow Lecture at St. Peter’s College, Adelaide, Australia.

138. 9.1.2014 – “Antidepressants: Mechanisms of action, pharmacogenomics, and new targets.” Invited Research Seminar at the Neuroscience Program, Institute of Molecular Medicine, School of Medicine, Faculdade de Medicina, University of Lisbon, Portugal

139. 9.05.2014 – “Leptin: From satiety to cognition. Summary of a 19-year longitudinal project.” Lecture at the EURON Neuroscience Course, Universidade do Minho, Braga, Portugal.

140. 12.13.2014 – “Leptin: From satiety to cognition. Summary of a 19-year longitudinal project.” Research Seminar, Cancer Centre, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.

141. 02.18.2015 – “Publishing in top journals – a key element to a successful career.” Tri-University Distinguished Guest Speaker, Adelaide, South Australia.

142. 04.29.2015 – “Overview of Mind & Brain.” Presentation to the Health & Medical Convenors Showcase. Adelaide, South Australia.

143. 09.02.2015 – “Precision medicine approaches to obesity and depression.” Presented at The University of Texas, Houston, Health Sciences Centre, Department of Psychiatry Grand Rounds.

144. 09.15.2015 – “Biomarkers of major depression.” Research Seminar presented at Ulsan University School of Medicine Department of Psychiatry, Asan Medical Centre, Seoul, South Korea.

145. 09.15.2015 – “How to get published in the world's top medical research journals.” Research Seminar presented at Ulsan University School of Medicine, Department of Psychiatry, Asan Medical Centre, Seoul, South Korea.

146. 09.17.2015 – “Biomarkers of major depression.” Research Seminar presented at Chonnam National University, Department of Psychiatry, Gwangju, South Korea.

147. 09.17.2015 – “How to get published in the world's top medical research journals.” Research Seminar presented at Chonnam National University, Department of Psychiatry, Gwangju, South Korea.

148. 10.13.2015 – “The search for biomarkers of major depression and antidepressant treatment response.” Grand Rounds presented at the Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, New Mexico.

149. 10.16.2015 – “The interface of obesity and major depression: An under-studied pathway from stress, obesity, and leptin, to mood and cognition.” Presented at the Cellular and Molecular Basis of Disease Seminar Series, University of New Mexico School of Medicine, Albuquerque, New Mexico.

150. 05.30.2016 – “Progress in the pharmacogenomics of major depressive disorder. Comparison and contrast with obesity.” Research Seminar presented at the Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Prilly-Lausanne, Switzerland

 

1. Licinio J. Co-inventor of United States patent 5,866,547 - Methods of neuroendocrine regulation of affective disorders, held jointly by the National Institutes of Health and Beth Israel Deaconess Medical Centre-Harvard Medical School.

2. Licinio, J: Co-inventor of UC Case N0.2004-109-1 - Novel Aspects of Antidepressant Action.

3. Licinio J: Co-inventor of a novel pharmacological treatment for obesity, leptin resistance and metabolic syndrome (Wong, ML; Licinio, J). SAHMRI, Provisional Patent Application number 2014900663; 02/28/2014.

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